Results 101 to 110 of about 20,765 (306)

The geometry and thickness of deformation-band fault core and its influence on sealing characteristics of deformation-band fault zones [PDF]

open access: yes, 2005
Deformation-band faults in high-porosity reservoir sandstones commonly contain a fault core of intensely crushed rock surrounding the main slip surfaces.
Thompson, L.B.   +2 more
core  

Structural heterogeneity and permeability in faulted eolian sandstone: Implications for subsurface modeling of faults [PDF]

open access: yes, 2002
We determined the structure and permeability variations of a 4 km-long normal fault by integrating surface mapping with data from five boreholes drilled through the fault (borehole to tens of meters scale).
Shipton, Zoe K.   +9 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Fault Injection Evaluation with Statistical Analysis

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
A critical aspect of securing cryptographic hardware is their resistance to Fault Injection (FI) attacks, which involve the successful injection of faults into the system in operation. Specifically, a hardware design must be resilient to wellestablished
Felix Uhle, Nicolai Müller, Amir Moradi
doaj   +1 more source

Calculation method for CO2 geological storage capacity of fault-block traps in Subei Basin based on safety considerations [PDF]

open access: yesYouqicang pingjia yu kaifa
To address the safety concerns associated with the CO2 geological storage process in fault-block traps of the Subei Basin, safety thresholds were systematically determined by integrating fault sealing capacity, caprock integrity, and wellbore stability ...
SUN Dongsheng, ZHANG Shunkang, WANG Zhilin, GE Zhengjun, LIN Bo
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

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