Results 91 to 100 of about 111,641 (296)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

On-going and future research at the Sulcis site in Sardinia, Italy. Characterization and experimentation at a possible future CCS pilot [PDF]

, 2017
National Italian funding has recently been allocated for the construction of a 350 MWe coal-fired power plant / CCS demonstration plant in the Sulcis area of SW Sardinia, Italy.
Barca, Jones, Livio Ruggiero, Maria Chiara Tartarello, Murru, Murru, Rossi, Sabina Bigi, Salvatore Lombardi, Stan E. Beaubien, Stefano Graziani   +10 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Fault Injection Evaluation with Statistical Analysis

Transactions on Cryptographic Hardware and Embedded Systems
A critical aspect of securing cryptographic hardware is their resistance to Fault Injection (FI) attacks, which involve the successful injection of faults into the system in operation. Specifically, a hardware design must be resilient to wellestablished
Felix Uhle, Nicolai Müller, Amir Moradi
doaj   +1 more source

Calculation method for CO2 geological storage capacity of fault-block traps in Subei Basin based on safety considerations [PDF]

Youqicang pingjia yu kaifa
To address the safety concerns associated with the CO2 geological storage process in fault-block traps of the Subei Basin, safety thresholds were systematically determined by integrating fault sealing capacity, caprock integrity, and wellbore stability ...
SUN Dongsheng, ZHANG Shunkang, WANG Zhilin, GE Zhengjun, LIN Bo
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Design of a Testing Tool Based on Fault Injection for Functional Safety [PDF]

E3S Web of Conferences
ISO 26262 provides testing requirements for functional safety development and testing to mitigate unacceptable risks arising from system functional failures. Fault injection plays a vital role in assessing system robustness and validating the efficacy of
Yan Hang, Li Shanshan, Lei Jianmei, Yan Tao, Tang Chunpeng   +4 more
doaj   +1 more source

User's guide to programming fault injection and data acquisition in the SIFT environment [PDF]

Described are the features, command language, and functional design of the SIFT (Software Implemented Fault Tolerance) fault injection and data acquisition interface software.
Elks, Carl R., Green, David F., Palumbo, Daniel L.   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source