Results 71 to 80 of about 20,765 (306)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fault-injection attack on countermeasure algorithms of RSA-CRT cryptosystem

网络与信息安全学报, 2019
As a widely-applied public-key cryptosystem in TLS, SSL and IPSec protocols, the security of RSA cryptosystem is of great importance. At FDTC 2014, Rauzy and Guilley proposed several improved countermeasure algorithms of RSA implementation based on ...
KONG Fanyu, LIU Xiaodong, ZHOU Dashui
doaj   +3 more sources

On how water injection may induce fault reactivation and slippage: A numerical method

Petroleum
During the water injection process in oil fields, the original stress equilibrium of faults might be disrupted by the large influx of fluids into the reservoir, resulting in movements.
Hao Yu, Yuheng Tuo, Tiejun Lin, Min Li, Zhanghua Lian   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Real time fault injection using enhanced OCD -- a performance analysis [PDF]

, 2006
Fault injection is frequently used for the verification and validation of dependable systems. When targeting real time microprocessor based systems the process becomes significantly more complex. This paper proposes two complementary solutions to improve
Ferreira, José M., Gustavo R. Alves, Andre Fidalgo, José M. Ferreira, Jose Ferreira, Fidalgo, André, Gustavo Alves, Alves, Gustavo R., André V. Fidalgo   +8 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Técnicas de inyección de fallos basadas en FPGAs para la evaluación de la tolerancia a fallos de tipo SEU en circuitos digitales [PDF]

, 2007
Este trabajo de tesis doctoral presenta nuevas técnicas de inyección de fallos transitorios en elementos de memoria, que permiten la evaluación del comportamiento de los complejos circuitos digitales actuales en presencia de fallos SEU (Single Event ...
Portela García, Marta
core  

System Reliability Evaluation Using Concurrent Multi-Level Simulation of Structural Faults [PDF]

, 2010
This paper provides a methodology that leverages state-of-the-art techniques for efficient fault simulation of structural faults together with transaction level modeling.
Hatami, N., Stefano Di Carlo, Baranowski, R., Wunderlich, H. J., Wunderlich, H.J., Zoellin, C. G., Michael E. Imhof, Hans-Joachim Wunderlich, Di Carlo, Stefano, Nadereh Hatami, Zoellin, C.G., Rafal Baranowski, Kochte, M. A., Imhof, M. E., Imhof, M.E., Paolo Prinetto, Prinetto, Paolo Ernesto, Michael A. Kochte, Kochte, M.A., Christian G. Zoellin   +19 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Virtual appliance size optimization with active fault injection

, 2012
Virtual appliances store the required information to instantiate a functional Virtual Machine (VM) on Infrastructure as a Service (IaaS) cloud systems. Large appliance size obstructs IaaS systems to deliver dynamic and scalable infrastructures according ...
Kacsuk, P, Terstyanszky, G., Terstyanszky, G, Kecskemeti, G., Kacsuk, P., Kecskemeti, G   +5 more
core   +1 more source