Results 71 to 80 of about 111,641 (296)

EFIC-ME: A Fast Emulation Based Fault Injection Control and Monitoring Enhancement

open access: yesIEEE Access, 2020
The security and dependability of embedded systems are increasing due to the sensitive and condensed structure of nanodevices. As the chip area shrinks and the technologies upgrade, the probability of Single Event Upset or Multi Bit Upset proliferate ...
Zain Ul Abideen, Muhammad Rashid
doaj   +1 more source

Safety assessment of automated vehicle functions by simulation-based fault injection [PDF]

open access: yes, 2017
As automated driving vehicles become more sophisticated and pervasive, it is increasingly important to assure its safety even in the presence of faults.
Amparan, Estibaliz   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Efficient Simulation of Structural Faults for the Reliability Evaluation at System-Level [PDF]

open access: yes, 2010
In recent technology nodes, reliability is considered a part of the standard design ¿ow at all levels of embedded system design. While techniques that use only low-level models at gate- and register transfer-level offer high accuracy, they are too ...
Baranowski, R.   +7 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Investigation of the Relationship of Earthquakes and Underground Waste Disposal in The El Dorado Area, Arkansas [PDF]

open access: yes, 1991
From December, 1983 to September, 1989 twelve small earthquakes were recorded for the El Dorado, Arkansas area. Magnitudes of these earthquakes were well below damaging levels.
Cox, Randel, VanArsdale, Roy B.
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Assessing Asymmetric Fault-Tolerant Software [PDF]

open access: yes, 2010
The most popular forms of fault tolerance against design faults use "asymmetric" architectures in which a "primary" part performs the computation and a "secondary" part is in charge of detecting errors and performing some kind of error processing and ...
Popov, P. T., Strigini, L.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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