Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Abnormal fault-recovery characteristics of the fault-tolerant multiprocessor uncovered using a new fault-injection methodology [PDF]
An investigation was made in AIRLAB of the fault handling performance of the Fault Tolerant MultiProcessor (FTMP). Fault handling errors detected during fault injection experiments were characterized.
Padilla, Peter A.
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Fault Injection with Multiple Fault Patterns for Experimental Evaluation of Demand-Controlled Ventilation and Heating Systems. [PDF]
Sensors (Basel), 2022 Kiamanesh B, Behravan A, Obermaisser R.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective There is growing interest in evaluating new strategies to delay or prevent posttraumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury. Methods Participants with a history of
Kevin Kennedy +9 more
wiley +1 more source
Measuring Fault Tolerance with the FTAPE fault injection tool [PDF]
, 1995 This paper describes FTAPE (Fault Tolerance And Performance Evaluator), a tool that can be used to compare fault-tolerant computers. The major parts of the tool include a system-wide fault injector, a workload generator, and a workload activity measurement tool. The workload creates high stress conditions on the machine.
Timothy K. Tsai, Ravishankar K. Iyer
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High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Arthritis Care &Research, EarlyView.Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source
In-circuit fault injector user's guide [PDF]
A fault injector system, called an in-circuit injector, was designed and developed to facilitate fault injection experiments performed at NASA-Langley's Avionics Integration Research Lab (AIRLAB).
Padilla, Peter A.
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A Tutorial on Hardware-Implemented Fault Injection and Online Fault Diagnosis for High-Speed Trains. [PDF]
Sensors (Basel), 2021 Yang X +4 more
europepmc +1 more source
Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology
Advanced Engineering Materials, EarlyView.We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham +7 more
wiley +1 more source
Experimental analysis of computer system dependability [PDF]
This paper reviews an area which has evolved over the past 15 years: experimental analysis of computer system dependability. Methodologies and advances are discussed for three basic approaches used in the area: simulated fault injection, physical fault ...
Iyer, Ravishankar, K., Tang, Dong
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