Results 31 to 40 of about 12,661 (215)

A Function-Level Fault Injection and Machine Learning Framework for Reliability Analysis

IEEE Access
Fault injection is widely used to evaluate the vulnerability of applications to soft errors. While hardware-level fault injection provides high accuracy, it is costly and complex, whereas software-level approaches are easier to apply but often less ...
Orhan Gunes, Sanem Arslan
doaj   +1 more source

Practical, Low-Cost Fault Injection Attacks on Personal Smart Devices

Applied Sciences, 2022
Fault attacks are traditionally considered under a threat model that assumes the device under test is in the possession of the attacker. We propose a variation on this model.
Shaked Delarea, Yossi Oren
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Research on Intelligent Diagnosis and Decision-Making Method for Oilfield Water Injection System Faults

IEEE Access
Water injection is a commonly used development method in oilfields. Water injection systems are large and complex, with horizontally and vertically interconnected pipeline networks often buried underground.
Ruijie Zhang, Wenting Yang, Jie Li, Shengliang Gao, Yan Wang, Sheng Gao   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Experimental investigation of fault reactivation mechanism and related seismic responses induced by hydraulic fracturing in mining areas

Meitan xuebao
Fault reactivation in mining areas can cause significant hazards, including rock bursts and mining-induced seismic events. Water injection and fracturing shows a great potential for fault reactivation regulation and seismicity mitigation.
Wu CAI, Linzhi WANG, Zhiyi WANG, LEE J. Hosking, Biao JIAO, Xingxing SHI   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Fault location method for hybrid MTDC system based on LCC signal injection strategy

Scientific Reports
A fault location method based on line commutation converter (LCC) signal injection strategy for hybrid multi-terminal direct current (MTDC) system is proposed to deter-mine the fault location after the permanent fault occurs and facilitate the line ...
Junjie Hou, Chao Gao, Yanfang Fan, Guobing Song, Xiaofang Wu, Chaowang Mu   +5 more
doaj   +1 more source

Dynamic Sealing Behavior of Sand Self-Juxtaposition Windows on a Trap-Bounding Fault in a Natural Gas Storage Site

Lithosphere, 2022
An understanding of across-fault seals is essential for planning an injection/production strategy for a fault-bounded gas storage site. In addition, it is more likely to permit lateral leakage for a fault with sand self-juxtaposition windows.
Xiaoling Zhang, Xiaofei Fu, Yachun Wang, Lingdong Meng, Ruishan Du, Shuxin Hong, Hongsong Yang, Xiandi Fu, Yabin Cheng, Jian Li, Baishuang Zhang   +10 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source