Results 41 to 50 of about 12,661 (215)
Identify Silent Data Corruption Vulnerable Instructions Using SVM
IEEE Access, 2019 Silent data corruption (SDC) is the most insidious and harmful result type of soft error. Identify program vulnerable instructions (PVIns) that are likely to cause SDCs is extremely significant on selective software-based protection techniques.
Na Yang, Yun Wang
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
On how water injection may induce fault reactivation and slippage: A numerical method
PetroleumDuring the water injection process in oil fields, the original stress equilibrium of faults might be disrupted by the large influx of fluids into the reservoir, resulting in movements.
Hao Yu +4 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Clock Glitch Fault Injection Attacks on AES Cipher
IEEE AccessSecure cryptographic systems like the Advanced Encryption Standard (AES) are critical in safeguarding sensitive data. Despite its robust design, AES is vulnerable to fault injection attacks, particularly via clock glitches on Field Programmable Gate ...
Yuvaraj Vagula +2 more
doaj +1 more source
Fault-injection attack on countermeasure algorithms of RSA-CRT cryptosystem
网络与信息安全学报, 2019 As a widely-applied public-key cryptosystem in TLS, SSL and IPSec protocols, the security of RSA cryptosystem is of great importance. At FDTC 2014, Rauzy and Guilley proposed several improved countermeasure algorithms of RSA implementation based on ...
KONG Fanyu, LIU Xiaodong, ZHOU Dashui
doaj +3 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source