Results 101 to 110 of about 252,496 (356)

Fault Detection and Isolation for a Secondary Loop Refrigeration System

, 2022
Agnes Poks, Markus Fallmann, Lorenz Fink, Lukas Rinnofner, Martin Kozek   +4 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Switching Control for Parameter Identifiability of Uncertain Systems

, 2015
This paper considers the problem of identifying the parameters of an uncertain linear system by means of feedback control. The problem is approached by considering time-varying controllers.
Battistelli, G., Tesi, P.
core   +1 more source

A Hamiltonian Approach to Fault Isolation in a Planar Vertical Take–Off and Landing Aircraft Model [PDF]

, 2015
L. H. Rodriguez-Alfaro, E. Alcorta-García, David Lara, Gerardo Romero   +3 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Assessing the Threshold of Need for Supplemental Damping in Seismic Base Isolation of Multistory Buildings

Shock and Vibration
The comprehension of the threshold for the need of supplemental dampers in the base isolation of multistory buildings could be beneficial in the advancement of the application of base isolation to achieve seismic safety. In this study, stick models of 1-,
Ali Reza Babaeian Amini, Peyman Narjabadifam, Gholam Reza Ostadi Asl, Samad Emamverdi, Shahram Derogar, Bertug Ozarisoy   +5 more
doaj   +1 more source

Fault detection and isolation of floating wind turbine pitch system based on Kalman filter and multi-attention 1DCNN

Systems Science & Control Engineering
In this paper, the fault detection and isolate problem is investigated for the pitch system of floating wind turbine. In the addressed system model, the system noises and measurement noises are correlated, and the measurement is affected by the missing ...
Yucheng Wang, Chuanbo Wen, Xianbin Wu
doaj   +1 more source

Flight test results of the strapdown hexad inertial reference unit (SIRU). Volume 2: Test report [PDF]

Results of flight tests of the Strapdown Inertial Reference Unit (SIRU) navigation system are presented. The fault tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers.
Bjorkman, W. S., Hruby, R. J.
core   +1 more source

Fault detection and isolation of malicious nodes in MIMO Multi-hop Control Networks

, 2013
A MIMO Multi-hop Control Network (MCN) consists of a MIMO LTI system where the communication between sensors, actuators and computational units is supported by a (wireless) multi-hop communication network, and data flow is performed using scheduling and ...
D'Innocenzo, A., Di Benedetto, M. D., Smarra, F.   +2 more
core   +1 more source