Results 131 to 140 of about 311,379 (303)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Time-varying characteristic analysis and parameter influence of transition resistance of tree-contact single-phase-to-ground fault

Diance yu yibiao
Tree-contact single-phase-to-ground fault (TSF) may ignite trees and cause fire, threatening the life and property of people. However, the fault characteristics of TSF are weak and difficult to identify, so it is urgent to further study the fault ...
NING Xin, ZHANG Hua, SHANG Hao, NING Wenjun   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Analysis and Modeling of Physical Evolution Mechanism for High-Resistance to Low-Resistance Grounding Faults in 10 kV Cable Joints

Energies
Currently, the lack of analysis and applicable circuit models for the evolution of cable joint faults is responsible for explosions or fire accidents in the distribution network system.
Yifeng Zhao, Yanqi Zeng, Ran Hu, Luliang Zhang, Gang Liu, Yihua Qian, Zhi Li   +6 more
doaj   +1 more source

Semiconductor technology program. Progress briefs [PDF]

The current status of NBS work on measurement technology for semiconductor materials, process control, and devices is reported. Results of both in-house and contract research are covered.
Bullis, W. M.
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A fault location method for DC distribution networks with DC circuit breaker and current limiter coordination

International Journal of Electrical Power & Energy Systems
To enhance the reliability of the protection system and accurately identify fault distances in DC networks, a fault location method is proposed, which leverages the coordination of existing DC circuit breakers (DCCBs) and current limiters.
Xiaoyong Cao, Jiaming Weng, Zaijun Wu, Dong Liu, Gaoming Li, Weinian Ouyang   +5 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Fault Location in Active Distribution Networks Using Improved Whale Optimization Algorithm

Iranian Journal of Electrical and Electronic Engineering, 2020
To realize the self-healing concept of smart grids, an accurate and reliable fault locator is a prerequisite. This paper presents a new fault location method for active power distribution networks which is based on measured voltage sag and use of whale ...
A. Bahmanyar, H. Borhani-Bahabadi, S. Jamali   +2 more
doaj  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source