Results 31 to 40 of about 1,525,201 (241)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Dependency modelling using fault tree analysis
, 1999 Dependency modelling using fault tree ...
Joanne Bechta Dugan (7120670) +1 more
core +4 more sources
Recent advances in fault tree analysis
, 1999 Recent advances in fault tree ...
Joanne Bechta Dugan (7120670) +1 more
core +4 more sources
Exploring best-matched embedding model and classifier for charging-pile fault diagnosis
Cybersecurity, 2023 The continuous increase of electric vehicles is being facilitating the large-scale distributed charging-pile deployment. It is crucial to guarantee normal operation of charging piles, resulting in the importance of diagnosing charging-pile faults.
Wen Wang +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Software fault tree analysis tool user's manual [PDF]
, 1986 The Software Fault Tree Analysis Tool allows the user to interactively modify the graphic representation of a fault tree. This manual describes the user interface of the tool.
Leveson, Nancy +3 more
core +1 more source
IEEE Access, 2020 In order to solve the problem of inaccurate fault location in the transmission network under some abnormal conditions, such as traveling wave location device faults, startup failure and time recording error, a novel traveling wave fault location method ...
Kun Yu +5 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source