Results 31 to 40 of about 10,460 (262)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

A Novel Traveling Wave Fault Location Method for Transmission Network Based on Directed Tree Model and Linear Fitting

open access: yesIEEE Access, 2020
In order to solve the problem of inaccurate fault location in the transmission network under some abnormal conditions, such as traveling wave location device faults, startup failure and time recording error, a novel traveling wave fault location method ...
Kun Yu   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Rapid Fault Diagnosis Method of Elevator System Based on Multiattribute Decision Making

open access: yesShock and Vibration, 2021
Fault tree analysis is often used in elevator fault diagnosis because of its simplicity and reliability. However, the traditional fault tree method has the problems of low efficiency due to ignoring location change of bottom events during troubleshooting.
Dapeng Niu   +4 more
doaj   +1 more source

Characteristic Quantity Analysis of Single-Phase Contact Tree Ground Fault of Distribution Network Overhead Lines

open access: yesEnergies, 2023
When the overhead line passes through the forest area, the conductor may contact the line to induce the tree-contact single-phase-to-ground fault (TSF), and the persistence of TSF may induce wildfires, bringing serious consequences.
Jianbo He   +6 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Quantum Fault Trees

open access: yes, 2022
12 pages, 7 figures, 2 ...
Silva, Gabriel San Martin   +2 more
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Application of Fault Tree Analysis Technique Based on Isograph to Railway Vehicles

open access: yes机车电传动, 2011
By taking the saloon door unexpectedly opening of the train on the main line as the top event, the fault tree based on Isograph was established and the fault tree analysis was carried out.
张丽娜, 武彤, 刘金安, 王金田
doaj  

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