Results 41 to 50 of about 17,558 (314)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Rapid Fault Diagnosis Method of Elevator System Based on Multiattribute Decision Making
Shock and Vibration, 2021 Fault tree analysis is often used in elevator fault diagnosis because of its simplicity and reliability. However, the traditional fault tree method has the problems of low efficiency due to ignoring location change of bottom events during troubleshooting.
Dapeng Niu +4 more
doaj +1 more source
Energies, 2023 When the overhead line passes through the forest area, the conductor may contact the line to induce the tree-contact single-phase-to-ground fault (TSF), and the persistence of TSF may induce wildfires, bringing serious consequences.
Jianbo He +6 more
doaj +1 more source
PFL: a Probabilistic Logic for Fault Trees
CoRR, 2023 Safety-critical infrastructures must operate in a safe and reliable way. Fault tree analysis is a widespread method used for risk assessment of these systems: fault trees (FTs) are required by, e.g., the Federal Aviation Administration and the Nuclear Regulatory Commission.
Stefano M. Nicoletti +3 more
openaire +4 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Application of Fault Tree Analysis Technique Based on Isograph to Railway Vehicles
机车电传动, 2011 By taking the saloon door unexpectedly opening of the train on the main line as the top event, the fault tree based on Isograph was established and the fault tree analysis was carried out.
张丽娜, 武彤, 刘金安, 王金田
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
机车电传动, 2021 At present, the line-side over-current faults of locomotives and EMUs traction system have the problem that the diagnosis and protection methods are single and the speci fic fault source cannot be accurately located. So a real-time diagnosis method based
Xueming LI +3 more
doaj
Fault tree analysis of fuzzy mechanical systems
, 1994 The fault tree techniques involve the decomposition of a system into a logic diagram or fault tree in which certain primary events lead to a specified top event that signifies the total failure of the system.
Rao, S.S, Sawyer, James P
core +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source