Results 181 to 190 of about 882,077 (297)

Observations of wildlife entrapment in cattle guards, with special consideration for special-status herpetofauna

California Fish and Wildlife Journal
Zachary P. Frey, Anny Peralta-García, Jorge H. Valdez-Villavicencio, Norma S. González-Gutiérrez, Jeff A. Alvarez   +4 more
doaj   +1 more source

Epizootological Survey and Identification of Helminth Fauna in Golden Jackals (<i>Canis aureus</i>) from Southern Kazakhstan. [PDF]

Biology (Basel)
Suleimenov M, Uakhit R, Berkinbay O, Omarov B, Zhanteliyeva L, Jussupbekova N, Baimukhanbetov Y, Khamchukova A, Manapov N, Alash A, Kiyan V.   +10 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Near complete 12S DNA reference library for the freshwater fish of French Guiana, northern Amazonian region. [PDF]

Sci Data
Brosse S, Cuenot Y, Condachou C, Coutant O, Covain R, Quartarollo G, Le Reun S, Vigouroux R, Murienne J.   +8 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sabethes mosquitoes (Diptera: Culicidae) associated with bamboo internodes in Pariquera-Açu and Cananeia, São Paulo State, Brazil. [PDF]

Rev Soc Bras Med Trop
Oliveira-Christe R, Medeiros-Sousa AR, Paula MB, Benar HF, Silva JDD, Oliveira LC, Marrelli MT.   +6 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cobamide-producing microbes as a model for understanding general nutritional interdependencies in soil food webs. [PDF]

Nat Commun
Zhang Q, Chen B, Zhang Z, Yu Y, Jin M, Lu T, Zhang Z, Pang Q, Xu N, Sun J, Chen J, Wang J, Zhu D, Qian H, Penuelas J, Zhu YG.   +15 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source