Results 61 to 70 of about 12,580 (199)

INVESTIGATION OF THE EFFECT OF FAVIPIRAVIR TREATMENT ON MORTALITY IN COVID-19 PATIENTS: EARLY PANDEMIC EXPERIENCE [PDF]

, 2023
Giriş: COVID-19 tedavisinde kullanılan ajanlardan biri olan favipiravirin diğer tedavilere üstünlüğü konusu halen tartışmalıdır. Bu çalışmayla, hastanemizde yatarak takip edilen favipiravir alan hastalarda, ilacın tedaviye başlangıçta ya da sonradan ...
Alkan, Sevil, Kayta, Safiye Bilge Güçlü, Kartal, Hakan, Şener, Alper, Doğan, Ebru   +4 more
core   +1 more source

Antiviral Resistance in Influenza: Clinical and Public Health Implications

Influenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Timely antiviral treatment and prevention can diminish the morbidity and mortality caused by influenza seasonal, zoonotic, and pandemic infections. However, the emergence of antiviral resistance threatens the utility of available agents and sometimes contributes to poor clinical outcomes.
Jinghao Nicholas Ngiam, Matthew Chung Yi Koh, Frederick G. Hayden   +2 more
wiley   +1 more source

New insights into electronic and adsorption energies of metallofullerenes C19M

Results in Materials, 2023
A comprehensive electronic investigation was carried out by G09W program to provide new insights into the adsorption energies of metallofullerenes C19M (M = Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu and Zn). In this regard, the DFT calculations were performed on
A.A. El-Barbary, I.F.M. AL-Dosari
doaj   +1 more source

Streamlined Synthesis and Structure–Activity Relationship Analysis of 2‐Amidothiophene‐3‐Carboxamides Targeting Influenza Polymerase PA‐PB1 Heterodimerization

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
Development of a three‐step synthesis and replacement of the cycloheptyl moiety in cycloheptathiophene‐3‐carboxamide derivatives revealed how thiophene C‐5 substitutions modulate PA–PB1 inhibition, antiviral potency, and water solubility. The phenyl analog 9 delivered sub‐µM potency across multiple IV strains, while the methyl analog 5 achieved the ...
Tommaso Felicetti, Alessia Zago, Andrea Astolfi, Giuseppe Manfroni, Stefano Sabatini, Maria Letizia Barreca, Oriana Tabarrini, Arianna Loregian, Serena Massari   +8 more
wiley   +1 more source

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

A highly sensitive and green electroanalytical method for the determination of favipiravir in pharmaceutical and biological fluids

BMC Chemistry, 2023
Background Favipiravir is currently used for the treatment of coronavirus disease-2019 (COVID-19). Objective A highly sensitive and eco-friendly electroanalytical method was developed to quantify favipiravir.
Heba M. El-Sayed, Hisham Ezzat Abdellatef, Hassan A. M. Hendawy, Omar M El-Abassy, Hany Ibrahim   +4 more
doaj   +1 more source

Sinusbradycardia mint lehetséges favipiravir-mellékhatás [PDF]

, 2022
A koronavírus–19-pandémia hatalmas kihívás az egészségügyi ellátórendszerek számára. A hatékony kezelés iránti igény felerősítette a terápiás megoldásokra való törekvéseket.
Szigeti, József, József Szigeti
core   +1 more source

Favipiravir Treatment Prolongs Survival in a Lethal BALB/c Mouse Model of Ebinur Lake Virus Infection

Viruses
Orthobunyavirus is the largest and most diverse genus in the family Peribunyaviridae. Orthobunyaviruses are widely distributed globally and pose threats to human and animal health.
Jingke Geng, Nanjie Ren, Cihan Yang, Fei Wang, Doudou Huang, Sergio Rodriguez, Zhiming Yuan, Han Xia   +7 more
doaj   +1 more source

Detailed Analyses of Molecular Interactions between Favipiravir and RNA Viruses In Silico

Viruses, 2022
There are currently no antiviral agents for human metapneumovirus (HMPV), respiratory syncytial virus (RSV), mumps virus (MuV), or measles virus (MeV).
Tatsuya Shirai, Mitsuru Sada, Takeshi Saraya, Daisuke Kurai, Soyoka Sunagawa, Haruyuki Ishii, Hirokazu Kimura   +6 more
doaj   +1 more source

Chitosan–Alginate Polyelectrolyte Systems: From Classical Release Models to the D‐PARMO Framework

Macromolecular Materials and Engineering, Volume 311, Issue 5, May 2026.
Classical empirical models fail to predict the dynamic in vivo behavior of chitosan‐alginate nanocarriers. Bridging this translational gap, the novel D‐PARMO framework replaces purely descriptive curve‐fitting with a mechanistically informed operational model.
Parastoo Rekab, Akeem Adeyemi Oladipo
wiley   +1 more source