Results 71 to 80 of about 13,127 (167)

A Sequence‐Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio   +15 more
wiley   +1 more source

Analytical Green Star Area for Sample Preparation (AGSA‐Prep) as a Comprehensive and Practice‐Oriented Metric

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Sample preparation is a critical, yet often environmentally burdensome, step in analytical chemistry. While Green Sample Preparation principles aim to mitigate this impact, existing assessment tools such as AGREEprep offer room for improvement in the assessment process.
Fotouh R. Mansour   +3 more
wiley   +1 more source

Safety and efficacy of favipiravir versus hydroxychloroquine in management of COVID-19: A randomised controlled trial

open access: yesScientific Reports, 2021
Favipiravir is considered a potential treatment for COVID-19 due its efficacy against different viral infections. We aimed to explore the safety and efficacy of favipiravir in treatment of COVID-19 mild and moderate cases.
Hany M. Dabbous   +10 more
doaj   +1 more source

Pengaruh Penggunaan Favipiravir terhadap Gejala Klinis Pasien Rawat Inap COVID-19 di RSU Santa Elisabeth Purwokerto [PDF]

open access: yes, 2022
Coronavirus Disease 2019 (COVID-19) adalah penyakit yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Salah satu terapi yang digunakan untuk COVID-19 yaitu antivirus favipiravir.
ASTUTI, Wiwi
core  

Effectiveness of Early Favipiravir Therapy in Hospitalised COVID-19 Patients

open access: yes, 2022
COVID-19 is a disease caused by a novel coronavirus with no specific, standard treatment. We investigated the clinical data of COVID-19 patients admitted to King Fahad Specialist Hospital (KFSH) in Buraydah by comparing the patients who were treated ...
Abdulrahman Alzahrani   +15 more
core   +1 more source

Randomized controlled trial of favipiravir, hydroxychloroquine, and standard care in patients with mild/moderate COVID-19 disease

open access: yesScientific Reports, 2022
Favipiravir has antiviral activity against influenza, West Nile virus, and yellow fever virus and against flaviviruses. The objective of this pilot study was to compare three arms: favipiravir; hydroxychloroquine; standard care (no specific SARS-CoV-2 ...
Manaf AlQahtani   +12 more
doaj   +1 more source

Favipiravir ve radyokontrast maddeler arası ilaç etkileşimlerinin değerlendirilmesi

open access: yes, 2023
COVID-19 olgularında Favipiravir sıkça tedavi rejimine eklenen bir ajandır. Favipiravir ve diğer COVID-19 tedavisinde kullanılan ajanlar arası ilaç etkileşimlerinin sıkça araştırıldığı görülmektedir. Buna karşın, tedavinin bir parçası olmamakla birlikte,
Sonay AYDIN
core   +1 more source

Antiviral Resistance in Influenza: Clinical and Public Health Implications

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 6, June 2026.
ABSTRACT Timely antiviral treatment and prevention can diminish the morbidity and mortality caused by influenza seasonal, zoonotic, and pandemic infections. However, the emergence of antiviral resistance threatens the utility of available agents and sometimes contributes to poor clinical outcomes.
Jinghao Nicholas Ngiam   +2 more
wiley   +1 more source

Streamlined Synthesis and Structure–Activity Relationship Analysis of 2‐Amidothiophene‐3‐Carboxamides Targeting Influenza Polymerase PA‐PB1 Heterodimerization

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
Development of a three‐step synthesis and replacement of the cycloheptyl moiety in cycloheptathiophene‐3‐carboxamide derivatives revealed how thiophene C‐5 substitutions modulate PA–PB1 inhibition, antiviral potency, and water solubility. The phenyl analog 9 delivered sub‐µM potency across multiple IV strains, while the methyl analog 5 achieved the ...
Tommaso Felicetti   +8 more
wiley   +1 more source

Electrooxidation of favipiravir: Optimization by response surface management [PDF]

open access: yes, 2023
Lisansüstü Eğitim Enstitüsü, Çevre Mühendisliği Ana Bilim Dalı, Çevre Mühendisliği Bilim Dalı2020 yılı Aralık ayında Çin' in Wuhan kentinde ortaya çıkan ve tüm dünyaya yayılan ve günümüzde hala devam eden Koronavirüs salgını çevre ve insan sağlığı ...
Özdeş, Resul
core  

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