Results 81 to 90 of about 12,580 (199)
Intranasal favipiravir in experimental rabies infection due to different variants
A raiva é uma doença zoonótica, altamente letal, transmitida por mamíferos, com rápida progressão viral e evolução clínica, sem protocolo terapêutico eficaz até o momento, o que incita a busca de um antiviral mais eficiente.
Ribeiro, Bruna Letícia Devidé
core
Favipiravir-resistant influenza A virus shows potential for transmission [PDF]
Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage in presence of drug with two mutations: K229R ...
Zhou, Jie +25 more
core +1 more source
Favipiravir tautomerism: a theoretical insight [PDF]
There is no experimental information about the tautomerism of Favipiravir (T-705). Therefore, its tautomeric state was predicted by using density functional theory in gas phase and in solution (toluene, acetonitrile and water). The results have shown that, in neutral state, the enol form is strongly dominating in both gas phase and solution.
openaire +2 more sources
Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man +7 more
wiley +1 more source
Determining the mutation bias of favipiravir in influenza using next-generation sequencing
Favipiravir is a broad-spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen but the precise mutation bias that favipiravir induces in influenza virus RNAs has not been ...
Lackenby, Angie +8 more
core +1 more source
Agam, Vora, Mangesh, Tiwaskar
openaire +3 more sources
Lipid and food structure determine when and how macro‐ and micronutrients become bioaccessible. This review compares lipid bioaccessibility from engineered emulsions, breast milk, infant formula, and meat and meat mimics, which couples the effect of cooking temperature on lipid bioaccessibility in meat and eggs. ABSTRACT Food structure has emerged as a
Michael A. Rogers, Amanda J. Wright
wiley +1 more source
A Retrospective Analysis of Treatment of Covid-19 with Favipiravir
One of the potential therapeutic agents for treating COVID-19 is favipiravir (FPV). This retrospective study compared the treatment of COVID-19 with (FVP group) or without (control group) favipiravir.
Utegenova,Aigul +5 more
core +1 more source
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka +1 more
wiley +1 more source
Favipiravir as RNA Polymerase Dependent (Rdrp) in COVID-19
Coronavirus disease 2019 or Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a new virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This disease became a pandemic and is being discussed around world because it has
Suharto, Fadel Fikri
core

