Results 101 to 110 of about 2,100,160 (252)

Comparison of neurological outcomes between out-of-hospital cardiac arrest due to anaphylaxis and cardiac causes: a nationwide population-based observational study

open access: yesBMJ Open
Objective To compare the neurological outcomes of out-of-hospital cardiac arrest due to anaphylaxis (OHCA-A) and cardiac causes (OHCA-C).Design Retrospective observational study.Setting Japanese nationwide dataset from 2012 to 2021.Participants In total,
Takashi Shiga   +5 more
doaj   +1 more source

Low admission serum albumin as prognostic determinant of 30-day case fatality and adverse functional outcome following acute ischemic stroke

open access: yesThe Pan African Medical Journal, 2013
INTRODUCTION: Over 80% of stroke deaths occur in low-income and middle-income regions of the world. Identification of predictors of mortality is vital so that prompt therapeutic measures could be instituted to improve outcome.
Sani Abubakar   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The frequency distribution of the lesion patterns in the different experimental groups shows a trend to a more favourable outcome (pattern C) in the combined treatment groups.

open access: yes, 2020
The frequency distribution of the lesion patterns in the different experimental groups shows a trend to a more favourable outcome (pattern C) in the combined treatment groups.
Susanne Jäckel (8562117)   +8 more
core   +1 more source

Association between pupillary examinations and prognosis in patients with out-of-hospital cardiac arrest who underwent extracorporeal cardiopulmonary resuscitation: a retrospective multicentre cohort study

open access: yesAnnals of Intensive Care
Background In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival serve as common early indicator ...
Takuro Hamaguchi   +12 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Investigating Patient Outcome Measures in Mental Health [PDF]

open access: yes
This report examines the feasibility of incorporating patient outcomes in mental health into a productivity measure. It examines which outcome measures are most commonly used in mental health, the practical issues about collecting these outcome measures,
Rowena Jacobs
core  

A core outcome set for clinical trials in acute diarrhoea.

open access: yes, 2015
OBJECTIVE:Core outcome sets are the baseline for what should be measured in clinical research and, thus, should serve as a guide for what should be collected and reported.
Vandenplas Y   +7 more
core   +1 more source

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