Results 81 to 90 of about 2,100,160 (252)

Neurological outcome after extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: a systematic review and meta-analysis

Critical Care, 2020
Background In-hospital cardiac arrest (IHCA) is a major adverse event with a high mortality rate if not treated appropriately. Extracorporeal cardiopulmonary resuscitation (ECPR), as adjunct to conventional cardiopulmonary resuscitation (CCPR), is a ...
Benjamin Yaël Gravesteijn, Marc Schluep, Maksud Disli, Prakriti Garkhail, Dinis Dos Reis Miranda, Robert-Jan Stolker, Henrik Endeman, Sanne Elisabeth Hoeks   +7 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Binary logistic regression for predictors of a favourable Frenchay Activities Index (FAI) outcome at six years after stroke.

, 2015
a = at stroke onsetb = at three monthsBinary logistic regression for predictors of a favourable Frenchay Activities Index (FAI) outcome at six years after stroke.
Kerstin Tham (835373), Avvai Singam (835371), Charlotte Ytterberg (835372), Lena von Koch (34412)   +3 more
core   +1 more source

Risk factors for a non-favourable outcome after treated European Neuroborreliosis [PDF]

, 2011
Aim: To identify risk factors for a non-favourable long term outcome with respect to Health Related Quality of Life (HRQoL) and fatigue after treated Lyme Neuroborreliosis (LNB).
Herlofson, Karen, Ljøstad, Unn, Eikeland, Randi, Mygland, Åse   +3 more
core   +1 more source

Progressive multifocal leucoencephalopathy in an immunocompetent patient with favourable outcome. A case report

BMC Neurology, 2010
Background To report the clinical course of PML in an apparently immunocompetent patient treated with cidofovir. Case Presentation A 35-year-old immunocompetent man who developed progressive hemianopsia, aphasia, and limb weakness underwent repeated MRI ...
Mørk Sverre J, Rinaldo Christine H, Storstein Anette, Glad Solveig, Naess Halvor, Myhr Kjell-Morten, Hirsch Hans   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis

, 2009
CCAAT/enhancer binding protein alpha (CEBPA) mutations in AML are associated with favourable prognosis and are divided into N- and C-terminal mutations. The majority of AML patients have both types of mutations. We assessed the prognostic significance of
Pabst, T, M Eyholzer, J Fos, Fos, J, B U Mueller, Mueller, B U, Eyholzer, M, T Pabst   +7 more
core   +1 more source

Conceptual fusion of the logical framework approach and outcome mapping [PDF]

, 2009
This paper describes the rational for and the process of creating a fusion model incorporating OM and LFA.
Roduner, Daniel, Ambrose, Kaia
core   +1 more source