Results 81 to 90 of about 496,947 (301)

Prehospital cardiopulmonary resuscitation duration and neurological outcome after out-of-hospital cardiac arrest among children by location of arrest: a Nationwide cohort study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Little is known about the associations between the duration of prehospital cardiopulmonary resuscitation (CPR) by emergency medical services (EMS) and outcomes among paediatric patients with out-of-hospital cardiac arrests (OHCAs).
Haruka Shida, Tasuku Matsuyama, Kosuke Kiyohara, Tetsuhisa Kitamura, Takefumi Kishimori, Takeyuki Kiguchi, Chika Nishiyama, Daisuke Kobayashi, Satoe Okabayashi, Tomonari Shimamoto, Takashi Kawamura, Taku Iwami   +11 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Neurological outcome after extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: a systematic review and meta-analysis

Critical Care, 2020
Background In-hospital cardiac arrest (IHCA) is a major adverse event with a high mortality rate if not treated appropriately. Extracorporeal cardiopulmonary resuscitation (ECPR), as adjunct to conventional cardiopulmonary resuscitation (CCPR), is a ...
Benjamin Yaël Gravesteijn, Marc Schluep, Maksud Disli, Prakriti Garkhail, Dinis Dos Reis Miranda, Robert-Jan Stolker, Henrik Endeman, Sanne Elisabeth Hoeks   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Adapting the Litterman prior for cointegrated VARs [PDF]

The paper presents a novel prior for Bayesian VAR models, characterized by explicit modelling of cointegration that avoids certain unattractive restrictive properties of the priors used previously. The potential of the prior for easy elicitation from the
Michal Markun
core  

Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care : systematic review and network meta-analysis [PDF]

, 2014
Peer reviewedPublisher ...
Glen, John, MacLennan, Graeme, Price, Richard, SuDDICU Collaboration   +3 more
core   +1 more source

Favourable pregnancy outcome after endometrectomy for a Robert's uterus

Journal of Obstetrics and Gynaecology, 2011
Robert's uterus is an uncommon Mullerian anomaly first described by Robert (1970), which results in an asymmetric septate uterus.
M, Vural, S, Yildiz, H, Cece, H, Camuzcuoglu   +3 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Intentional Use of Service Recovery Strategies to Influence Consumer Emotion, Cognition and Behaviour [PDF]

, 2007
Service recovery strategies have been identified as a critical factor in the success of. service organizations. This study develops a conceptual frame work to investigate how specific service recovery strategies influence the emotional, cognitive and ...
A. Palmer, R. Beggs, C. Keown-McMullan, A.K. Smith, R.N. Bolton, A.K. Smith, R.N. Bolton, J. Wagner, A.S. Mattila, C.A. Enz, A.S. Mattila, J. Wirtz, B.A. Sparks, J.R. McColl-Kennedy, C. Gronroos, C. Gronroos, C.H. Lovelock, D.M. Szymanski, D.H. Henard, D.T. Nguyen, J.R. McColl-Kennedy, H.M. Weiss, J. Pallant, J. Wirtz, A.S. Mattila, J.C. Huefner, B.L. Parry, C.R. Payne, S.D. Otto, S.C. Huff, M.J. Swenson, H.K. Hunt, J.C. Huefner, H.K. Hunt, J.F. Hair, R.E. Anderson, R.L. Tatham, W.C. Black, J.G. Maxham, J.O. Nunnally, J.P. Forgas, J.R. McColl-Kennedy, B.A. Sparks, K. Schoefer, C. Ennew, K. Woo, H.K.Y. Fock, K.D. Hoffman, S.W. Kelley, H.M. Rotalsky, K.P. Scherer, G. Caechi, L. Dube, K. Menon, L.C. Harris, K.L. Reynolds, L.C. Harris, K.L. Reynolds, L.L. Price, E.J. Arnould, F. Bardhi, L.R. Kahle, P. Kennedy, M. Davidow, M. Johnson, G.M. Zinkham, M.A. McCollough, L.L. Berry, M.S. Yadav, M.J. Bitner, A.R. Hubbert, M.J. Bitner, B.H. Booms, L.A. Mohr, M.J. Bitner, B.H. Booms, M.S. Tetreault, M.L. Richins, N.K. Allison, N.N. Bechwati, M. Morrin, O. Freestone, V.-W. Mitchell, P. Shaver, J. Schwartz, D. Kirson, C. O’Connor, R. Bougie, R. Pieters, M. Zeelenberg, R. Hill, R.A. Fullerton, G. Punj, R.A. Fullerton, G. Punj, R.A. Spreng, G.D. Harrell, R.D. Mackoy, R.J. Bennett, S.L. Robinson, R.L. Oliver, R.L. Oliver, R.L. Oliver, R.L. Oliver, J.E. Swan, R.P. Bagozzi, M. Gopinath, P.U. Nyer, R.P. Fisk, S.W. Brown, M.J. Bitner, R.P. Hill, J.C. Ward, S. Fullerton, K.B. Kerch, H.R. Dodge, S.S. Tax, S.W. Brown, M. Chandrashekaran, S.W. Kelley, K.D. Hoffman, M.A. Davis, T. Kunin, T. Kunin, T.W. Andreassen, W.J. Lundstrom, L.M. Lamont, W.R. Forrester, M.F. Maute   +61 more
core   +2 more sources