Results 61 to 70 of about 2,855 (182)

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna   +5 more
wiley   +1 more source

Clinical Characteristics and Genetic Analysis of a Family With Birt-Hogg-Dubé Syndrome and Congenital Contractural Arachnodactyly

open access: yesFrontiers in Genetics, 2022
Background: Birt-Hogg-Dubé (BHD) syndrome and congenital contractural arachnodactyly (CCA) or Beals-Hecht syndrome are clinically rare autosomal dominant genetic diseases.
Jiayong Qiu   +7 more
doaj   +1 more source

Transcriptomic and microRNA Profiling Suggest a Candidate RIPPLY1–cfa‐miR‐187 Relationship in Canine Mammary Gland Tumours From Dogs With Confirmed Metastasis

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 3, Page 631-642, September 2026.
ABSTRACT Canine mammary gland tumours (MGT) represent a common malignancy in intact female dogs, with a high metastasis rate approaching 50% and a poor prognosis. However, metastasis‐related genes remain largely unelucidated. Accordingly, we aimed to identify differentially expressed mRNAs and miRNAs in primary canine MGT tissues from dogs with or ...
Shaohsu Wang   +14 more
wiley   +1 more source

Characterization of a Plastoglobule-Localized SOUL4 Heme-Binding Protein in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2020
Heme plays an active role in primary plant metabolic pathways as well as in stress signaling. In this study, we characterized the predicted heme-binding protein SOUL4.
Venkatasalam Shanmugabalaji   +2 more
doaj   +1 more source

Therapeutic and Predicted Significance of PKLR in Patients With Cholangiocarcinoma

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Cholangiocarcinoma (CCA) is a highly heterogeneous malignancy with a poor prognosis. However, the molecular mechanisms underlying CCA and its treatment options remain unclear and limited. Aims This study aims to identify novel prognostic biomarkers and potential therapeutic targets for CCA through transcriptomics and whole‐exome ...
Biyan Gong   +7 more
wiley   +1 more source

Forelimb contractures, reduced muscle mass and altered muscle morphology in P0 Fbn2 null mice.

open access: yes, 2015
(A)Fbn2 null forelimb contractures from P0 to P8. (B) Representative H&E stained P0 forearm cross sections from the same approximate position in the forearm. The cross sections are composites of multiple micrographs.
Francesco Ramirez (22223)   +8 more
core   +1 more source

Mutation Analysis of Fibrillin-2 (FBN2) and Microfibril Associated Protein-3 (MFAP-3): Two Genes Associated with Congenital Contractural Arachnodactyly (CCA), also known as Beal\u27s Syndrome [PDF]

open access: yes, 1996
Congenital Contractural Arachnodactyly (CCA), also known as Beal\u27s syndrome, is an autosomal dominant disorder characterized by multiple congenital joint contractures, arachnodactyly, dolichostenomelia, and scoliosis with only rare ocular or ...
Babcock, Darcie
core   +1 more source

Ovarian Extracellular Matrix Mechanics Regulate Oocyte‐Follicle Interactions During Female Reproductive Aging

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Hydrogel culture mimicking young and aged ovarian stromal stiffness recapitulates key features of reproductive aging, including impaired follicle growth, transzonal projections (TZPs), and oocyte quality. Silencing Smad7 rescues TZPs and oocyte quality in stiff hydrogels, identifying ECM mechanics as a driver and therapeutic target in ovarian aging ...
Xingyu Shen   +10 more
wiley   +1 more source

MyGene2 automated match report: FBN2

open access: yes, 2017
MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If
openaire   +1 more source

Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging. [PDF]

open access: yes, 2022
Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop-extruding cohesins, but the live dynamics of loop formation and stability remain unknown. Here, we directly visualized chromatin looping at the Fbn2 TAD in
Hansen, Anders S   +23 more
core   +1 more source

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