Results 61 to 70 of about 2,722 (177)
Frontiers in Genetics, 2022 Background: Birt-Hogg-Dubé (BHD) syndrome and congenital contractural arachnodactyly (CCA) or Beals-Hecht syndrome are clinically rare autosomal dominant genetic diseases.
Jiayong Qiu +7 more
doaj +1 more source
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Advanced Science, Volume 13, Issue 17, 23 March 2026.Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Forelimb contractures, reduced muscle mass and altered muscle morphology in P0 Fbn2 null mice.
, 2015 (A)Fbn2 null forelimb contractures from P0 to P8. (B) Representative H&E stained P0 forearm cross sections from the same approximate position in the forearm. The cross sections are composites of multiple micrographs.
Francesco Ramirez (22223) +8 more
core +1 more source
Characterization of a Plastoglobule-Localized SOUL4 Heme-Binding Protein in Arabidopsis thaliana
Frontiers in Plant Science, 2020 Heme plays an active role in primary plant metabolic pathways as well as in stress signaling. In this study, we characterized the predicted heme-binding protein SOUL4.
Venkatasalam Shanmugabalaji +2 more
doaj +1 more source
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
International Journal of Cosmetic Science, Volume 48, Issue 1, Page 186-199, February 2026.Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier +9 more
wiley +1 more source
Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging. [PDF]
, 2022 Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop-extruding cohesins, but the live dynamics of loop formation and stability remain unknown. Here, we directly visualized chromatin looping at the Fbn2 TAD in
Hansen, Anders S +23 more
core +1 more source
Advanced Science, Volume 13, Issue 3, 14 January 2026.ToCV‐encoded p22 targets chloroplast plastoglobules (PGs) via directly binding PG structural protein FBN1.1, reducing the size of PG and inhibiting α‐tocopherol biosynthesis via competing with tocopherol cyclase (VTE1). Consequently, the elevated chloroplast ROS not only creates a suitable cellular environment for efficient ToCV infection but also ...
Sijia Liu +8 more
wiley +1 more source
Mediators of Inflammation, 2022 Menopause is accompanied with an increased risk of cardiovascular disease. DNA methylation may have a significant impact on postmenopausal women’s development of coronary heart disease.
Xiao Zhong +5 more
doaj +1 more source
Journal of Orthopaedic Research, Volume 44, Issue 1, January 2026.ABSTRACT Rotator cuff disorders are common in the aging population, often leading to pain, disability, and reduced quality of life. Age‐associated changes can occur disproportionately in regions of high mechanical stress, such as the insertion site of the supraspinatus tendon, leading to increased injury rates and tendinopathies.
Michael S. DiStefano +6 more
wiley +1 more source