Results 81 to 90 of about 2,722 (177)

Limb organ cultures of heterozygous and Fbn2 null forearm muscles.

open access: yes, 2015
(A) H & E sections of Fbn2 null muscle cultured with or without Noggin (left) and quantitation of myofibers with central nuclei (right). (B) H & E sections of control forearms (Fbn2+/-) cultured with or without BMP-7 (left) and quantitation of myofibers ...
Francesco Ramirez (22223)   +8 more
core   +1 more source

FBN2 Silencing Recapitulates Hypoxic Conditions and Induces Elastic Fiber Impairment in Human Dermal Fibroblasts

open access: yes, 2022
International audienceMost chronic wounds are characterized by varying degrees of hypoxia and low partial pressures of O2 that may favor the development of the wound and/or delay healing. However, most studies regarding extracellular matrix remodeling in
Minville-Walz, Mélaine   +13 more
core   +1 more source

MyGene2 automated match report: FBN2

open access: yes, 2017
MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If
openaire   +1 more source

Role of Angiotensin Receptor Blockers on Cardiovascular Protection in Marfan Syndrome: A Literature Review

open access: yesHealth Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Marfan Syndrome (MFS) is a hereditary connective tissue disorder with severe cardiovascular complications, including aortic aneurysms and dissections. Current therapies, such as beta‐blockers, have limitations in preventing disease progression.
Hashim Mohamed Siraj   +9 more
wiley   +1 more source

Engineered Decellularized Matrix Hydrogels with Crypt–Villus Topography for Forming Functional Intestinal Epithelium

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
A decellularized matrix hydrogel is fabricated with intestinal crypt/villus topography using an inverse‐molding technique over a sacrificial hydrogel with rapid and autonomous dissolution. Integrating a biofabrication workflow with a matrix with proper stiffness, bioactivity, and topography creates a functional intestinal barrier suitable for drug ...
Ngoc Ha Luong   +3 more
wiley   +1 more source

Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice

open access: yesG3: Genes, Genomes, Genetics, 2018
Positional cloning of ENU-induced mutations has traditionally relied on analysis of polymorphic variation between two strains. In contrast, the application of whole-genome sequencing (WGS) has enabled gene discovery in mutant lines maintained on an ...
Krista A. Geister   +2 more
doaj   +1 more source

The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone

open access: yesAging Cell, Volume 24, Issue 12, December 2025.
scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal   +12 more
wiley   +1 more source

FIBRILLINS IN TENDON

open access: yesFrontiers in Aging Neuroscience, 2016
Tendons among connective tissue, mainly collagen, contain also elastic fibres made of fibrillin 1, fibrillin 2 and elastin that are broadly distributed in tendons and represent 1-2% of the dried mass of the tendon.
Betti Giusti, Guglielmina Pepe
doaj   +1 more source

Mp mapped to a balanced 660 kb inversion on chromosome 18 disrupting Fbn2 and Isoc1.

open access: yes, 2013
(A) Haplotype analysis using DNA samples from 3rd backcross (from parental strain C3H onto C57BL/6J) Mp/+ animals (n = 43) for four microsatellite markers on chromosome 18 revealed there had been no meiotic recombination events between markers D18MIT74 ...
Douglas R. Keene (46430)   +12 more
core   +1 more source

Assessing the impact of storage conditions on RNA from human saliva and its application to the identification of mRNA biomarkers for asthma

open access: yesFrontiers in Molecular Biosciences
Introduction: Human saliva was used to develop non-invasive liquid biopsy biomarkers to establish saliva as an alternate to blood and plasma in translational research.
Poorna Manasa Bhamidimarri   +10 more
doaj   +1 more source

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