Results 71 to 80 of about 4,235 (189)

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

open access: yesImmunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle   +6 more
wiley   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, Volume 48, Issue 1, Page 186-199, February 2026.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

Identification of an Epigenetic Signature for Coronary Heart Disease in Postmenopausal Women’s PBMC DNA

open access: yesMediators of Inflammation, 2022
Menopause is accompanied with an increased risk of cardiovascular disease. DNA methylation may have a significant impact on postmenopausal women’s development of coronary heart disease.
Xiao Zhong   +5 more
doaj   +1 more source

Radiomic profiling of clear cell renal cell carcinoma reveals subtypes with distinct prognoses and molecular pathways

open access: yesTranslational Oncology, 2021
Background: To identify radiomic subtypes of clear cell renal cell carcinoma (ccRCC) patients with distinct clinical significance and molecular characteristics reflective of the heterogeneity of ccRCC.
Peng Lin   +6 more
doaj   +1 more source

Chloroplast Fibrillin‐Mediated α‐Tocopherol Biosynthesis Impaired by a Virus to Enhance Infection and to Improve Drought Tolerance

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
ToCV‐encoded p22 targets chloroplast plastoglobules (PGs) via directly binding PG structural protein FBN1.1, reducing the size of PG and inhibiting α‐tocopherol biosynthesis via competing with tocopherol cyclase (VTE1). Consequently, the elevated chloroplast ROS not only creates a suitable cellular environment for efficient ToCV infection but also ...
Sijia Liu   +8 more
wiley   +1 more source

A novel FBN2 mutation cosegregates with congenital contractural arachnodactyly in a five‐generation Chinese family

open access: yesClinical Case Reports, 2018
Key Clinical Message We identified a novel heterozygous mutation (c.4177T>G and p.Cys1393Gly) in FBN2 that cosegregated with congenital contractural arachnodactyly (CCA) in a five‐generation Chinese family.
Shiyuan Zhou   +8 more
doaj   +1 more source

Additive versus abelian 2-representations of fiat 2-categories [PDF]

open access: yes, 2014
We study connections between additive and abelian 2-rep- resentations of fiat 2-categories, describe combinatorics of 2-categories in terms of multisemigroups and determine the annihilator of a cell 2- representation.
Mazorchuk, Volodymyr, Miemietz, Vanessa
core  

Murine Supraspinatus Tendons Demonstrate Aging‐Related Changes in Multiscale Mechanics, Structure, and Gene Expression

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Rotator cuff disorders are common in the aging population, often leading to pain, disability, and reduced quality of life. Age‐associated changes can occur disproportionately in regions of high mechanical stress, such as the insertion site of the supraspinatus tendon, leading to increased injury rates and tendinopathies.
Michael S. DiStefano   +6 more
wiley   +1 more source

Establishment of a Beals syndrome patient-derived human induced pluripotent stem cell line HELPi001-A

open access: yesStem Cell Research, 2019
The human induced pluripotent stem cell line HELPi001-A was derived from peripheral blood mononuclear cells (PBMC) of a 35-year-old female Beals syndrome patient carrying a heterozygous FBN2c.728 T > C mutation.
Hao Liu   +6 more
doaj   +1 more source

Defining the Extracellular Matrix of Rhabdomyosarcoma

open access: yesFrontiers in Oncology, 2021
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy, and surgical resection; nevertheless ...
Xiaolei Lian   +17 more
doaj   +1 more source

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