Results 51 to 60 of about 1,252,619 (143)

The role of Fcγ Receptor in activation of NF-κB in Follicular Dentritic Cells

, 2013
The purpose of this project was to determine the reason why the transcription factor NF-κB is not activated when immune complexes (especially those containing HIV) bind to its Fcγ-Receptor, but is activated in FDC’s when the same immune complex (IC ...
Scoville, Jonathan, Burton, Dr. Gregory F.   +1 more
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Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2074-2081, October 2026.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

The inhibitory effects of intravenous administration of rabbit immunoglobulin G on airway inflammation are dependent upon Fcγ receptor IIb on CD11c+ dendritic cells in a murine model

, 2010
Summary Immunoglobulins (Igs) play important immunomodulatory effects on allergic asthma. Among these, IgG has been reported to regulate allergic inflammation in previous studies about immunotherapy and intravenous immunoglobulin therapy ...
Y Funada, A Masuda, T Azuma, M Yamamoto, Y Ishikawa, K Kobayashi, K Nakata, T Takai, M Yoshida, Y Nishimura, Y Kotani   +10 more
core   +1 more source

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt, Enzo Manchon, Ming Wu, Helene Le Buanec, Pauline Bataille, Emmanuelle Bourrat, Jean‐David Bouaziz, Nabila Jabrane‐Ferrat, Reem Al‐Daccak   +8 more
wiley   +1 more source

Genetic variation in Fcγ receptor IIa and risk of coronary heart disease : negative results from two large independent populations [PDF]

, 2009
Background The role of the Fcgamma receptor IIa (FcgammaRIIa), a receptor for C-reactive protein (CRP), the classical acute phase protein, in atherosclerosis is not yet clear.
Hoffmann, Michael Marcus, Karakas, M., Hoffmann, M.M., Khuseyinova, N., Illig, Thomas, Bernhard Winkelmann, Karakas, Mahir, Thomas Illig, Vollmert, C., Christa Meisinger, Koenig, W., Mahir Karakas, März, Winfried, Caren Vollmert, Winkelmann, Bernhard, Meisinger, C., Winkelmann, B., Hoffmann, Michael M., Khuseyinova, Natalie, Natalie Khuseyinova, Rothenbacher, D., Illig, T., Bernhard O Böhm, Böhm, Bernhard O., Vollmert, Caren, Koenig, Wolfgang, Böhm, Bernhard Otto, Rothenbacher, Dietrich, Marz, W., Michael M Hoffmann, Meisinger, Christine, König, Wolfgang, Meisinger, Christa, Böhm, B.O., Dietrich Rothenbacher, Wolfgang Koenig, Winkelmann, Bernhard Rudolf, Winfried März, Winkelmann, Bernhard R.   +38 more
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Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
The immunosuppressive in OM Staphylococcus aureus employs multiple physical barriers to evade host immunity during skeletal infection, including biofilm formation on implant surfaces and necrotic bone tissues, invasion into the osteocyte lacuno‐canalicular network (OLCN), intracellular persistence within osteoblasts, osteoclasts, and osteocytes, and ...
Qingqiang Lei, Liangbin Lin, Peidong Pu, Jie Chen, Xianchao Su, Shubao Liu, Yanli Tong, Hui Yu   +7 more
wiley   +1 more source

FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance [PDF]

, 2017
For many years, disappointing results have been generated by many investigations, which have utilized a variety of immunologic strategies to enhance the ability of a patient’s immune system to recognize and eliminate malignant cells.
Del Principe, Maria Ilaria, Adriano Venditti, Maurillo, Luca, Lauro, D, Roberto Arriga, Maurillo, L, Arriga, R, Del Principe, Mi, Luca Maurillo, Lanzilli, Giulia, Sara Caratelli, Venditti, Adriano, Buccisano, F, Venditti, A, Giulia Lanzilli, Caratelli, Sara, Maria Ilaria Del Principe, Arriga, Roberto, Coppola, Andrea, Sconocchia, T, Ferrone, Soldano, Andrea Coppola, Coppola, A, Ferrone, S, Sconocchia, Tommaso, Sconocchia, Giuseppe, Caratelli, S, Davide Lauro, Sconocchia, G, Buccisano, Francesco, Lauro, Davide, Tommaso Sconocchia, Francesco Buccisano, Giuseppe Sconocchia, Lanzilli, G, Soldano Ferrone   +35 more
core   +1 more source

Glycoproteomic Signatures of IgG Subclass N‐Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies

MedComm, Volume 7, Issue 10, October 2026.
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu, Yanhong Li, Yingying Ling, Yinlan Wu, Jing Zhao, Lu Cheng, Chunyu Tan, Yi Zhang, Yong Zhang, Yi Liu   +9 more
wiley   +1 more source

Fcγ IIa receptor polymorphisms in Idiopathic Thrombocytopenic Purpura

, 2004
의학과/석사[한글] 여러 자가면역 질환에서 면역에 관계하는 수용체의 다형성과의 관련성에 대한 연구들이 보고되고 있으나 특발성 혈소판 감소증(Idiopathic Thrombocytopenic Purpura, ITP)과 수용체 다형성의 관계에 대해서는 아직 완전히 밝혀진 것이 없다.
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