Results 61 to 70 of about 1,252,619 (143)

Soluble FCγ receptors

, 1993
Soluble FCγ receptors have been identified in biological fluids of mice and humans. They are produced either by alternative splicing of the exon encoding the transmembrane region of the receptor (FcγRII) or by proteolytic cleavage at the cell membrane ...
Caroline Bouchard, Eric Tartour, Catherine Sautes, Claire Mathiot, Jerome Galon, Wolf H Fridman, Christophe Teillaud, Anne Astier, Jean-Luc Teillaud   +8 more
core   +1 more source

Bruton's Tyrosine Kinase Inhibitors: Mechanisms, Efficacy, Toxicities and Applications for the Treatment of Human Diseases

MedComm, Volume 7, Issue 10, October 2026.
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley   +1 more source

Using synthetic models to understand the detecting ability of ground‐penetrating radar for water‐conducting structures in the bedrock of formerly glaciated site

Near Surface Geophysics, Volume 24, Issue 5, Page 669-692, October 2026.
Abstract Utilizing synthetic models for the interpretation of ground‐penetrating radar (GPR) profiles can aid in the detection of hydrogeological structures by identifying their signatures. In this study, finite difference (FD) forward modelling was used to understand the detection ability of 50 MHz GPR for (1) the quaternary deposit–bedrock contact ...
Annika Katarina Åberg, Salla Eeva, Emilia Koivisto, Susanne Charlotta Åberg, Seija Kultti, Kirsti Korkka‐Niemi   +5 more
wiley   +1 more source

Abrogation of the Fcγ receptor IIA-mediated phagocytic signal by stem-loop Syk antisense oligonucleotides

, 1996
The role of Syk kinase in Fcγ receptor (FcγR) IIA-mediated phagocytosis was examined with two forms of antisense oligodeoxynucleotides (ODNs) designed to hybridize to human Syk mRNA.
Jong Gu Park, Da Cheng Wang, Sharon Hunter, Alan D Schreiber, Paul Chien, Mitsuhiro Matsuda   +5 more
core   +1 more source

Ultrasonic Vibration Assisted Laser Processing: A Hybrid Paradigm for Extreme Surface Enhancement

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Traditional laser processing techniques offer many advantages, but they often encounter limitations such as heat‐affected zones, recast layers, residual tensile stresses, and poor surface finish. The integration of ultrasonic vibration (UV) presents a promising hybrid approach to overcome these challenges by introducing beneficial effects like
Aziz Ul Hassan Mohsan, Xuedao Shu, Hu Zong, Su Zhao, Khamis Essa, Di Tie, Changyong Chen   +6 more
wiley   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

Physiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura, Takehito Sugasawa, Masaomi Nangaku, Imari Mimura   +3 more
wiley   +1 more source

Analysis of ATROSAB for binding to human soluble Fcγ receptors and human complement protein C1q and the lack of the induction of ADCC and CDC.

, 2013
Binding of immobilized ATROSAB and Trastuzumab to human soluble Fcγ receptor IA (a), Fcγ receptor IIB (b), Fcγ receptor IIIA (c), and human C1q (d).
Andreas Herrmann (362184), Eric Guenzi (447422), Klaus Pfizenmaier (47885), Timo Liebig (447421), Peter Scheurich (144993), Fabian Richter (447420), Roland E. Kontermann (235510)   +6 more
core   +1 more source

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

Chemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis, Héloïse Uhl, Florence Niedergang, Jacques Fattaccioli, Blaise Dumat, Jean‐Maurice Mallet   +5 more
wiley   +1 more source

Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor

, 2016
Structurally well-defined IgG-Fc glycoforms are highly demanded for understanding the effects of glycosylation on an antibody’s effector functions. We report in this paper chemoenzymatic synthesis and Fcγ receptor binding of an array of homogeneous IgG ...
Wei Huang (36889), Cishan Li (2144344), Hirofumi Ochiai (2144341), Guozhang Zou (1631764), Qiang Yang (135832), Lai-Xi Wang (266700)   +5 more
core   +1 more source

Fcγ receptor expression and function reflecting severity of joint inflammation in drug naïve early RA patients (n = 20).

, 2015
Abbreviations; MFI = mean fluorescence intensity, MS = morning stiffness, VAS = visual analogue scale, DAS = disease activity score, CRP = C-reactive protein, IC = immune complex, TJC = tender joint count, SJC = swollen joint count, TNFα = tumor necrosis
Peter Matt (799989), Sandra Kleinau (84244), Ulla Lindqvist (799990)   +2 more
core   +1 more source