Results 241 to 250 of about 446,586 (304)

Identification of the Linear Fc-Binding Site on the Bovine IgG1 Fc Receptor (boFcγRIII) Using Synthetic Peptides. [PDF]

Vet Sci
Wang R, Guo J, Li G, Wang X, Yang J, Li Q, Zhang G.   +6 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Antibody Fc receptor binding and T cell responses to homologous and heterologous immunization with inactivated or mRNA vaccines against SARS-CoV-2. [PDF]

Nat Commun
Cohen CA, Leung NHL, Kaewpreedee P, Lee KWK, Jia JZ, Cheung AWL, Cheng SMS, Mori M, Ip DKM, Poon LLM, Peiris JSM, Cowling BJ, Valkenburg SA.   +12 more
europepmc   +1 more source

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity. [PDF]

Nat Commun
Huang C, Zhu W, Li Q, Lei Y, Chen X, Liu S, Chen D, Zhong L, Gao F, Fu S, He D, Li J, Xu H.   +12 more
europepmc   +1 more source

TCF1highPD-1+Ly108+CD8+ T Cells Are Associated with Graft Preservation in Sensitized Mice Treated with Non-Fc Receptor-Binding CD3 Antibodies. [PDF]

Immunohorizons
Ota T, Goto R, Harada T, Forgioni A, Kanazawa R, Ganchiku Y, Kawamura N, Watanabe M, Fukai M, Shimamura T, Taketomi A.   +10 more
europepmc   +1 more source

iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma. [PDF]

Front Immunol
Dixon KJ, Snyder KM, Khaw M, Hullsiek R, Davis ZB, Matson AW, Shirinbak S, Hancock B, Bjordahl R, Hosking M, Miller JS, Valamehr B, Wu J, Walcheck B.   +13 more
europepmc   +1 more source

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Fc receptors

Current Opinion in Immunology, 1991
In the past year, significant progress in the area of Fc receptor biology has been made in three areas: identification of the protective FcR for serum IgG half-life (Brambell receptor), characterization of the mechanism(s) of inhibitory receptor Fc gamma RIIB signaling, and dissection of the in vivo roles of FcRs in inflammation.
J V, Ravetch, J P, Kinet
openaire   +4 more sources

IgG Fc Receptors

Annual Review of Immunology, 2001
Since the description of the first mouse knockout for an IgG Fc receptor seven years ago, considerable progress has been made in defining the in vivo functions of these receptors in diverse biological systems. The role of activating FcγRs in providing a critical link between ligands and effector cells in type II and type III inflammation is now well ...
J V, Ravetch, S, Bolland
openaire   +2 more sources

Fc Receptor Signaling

1994
Immune complex cross-linking of cell surface receptors for immunoglobulin (Ig) triggers pleiotropic cellular events that underpin a wide variety of immune responses. In this fashion receptors for immunoglobulin form a molecular bridge between the humoral and cellular immune responses.
D, Brooks, J V, Ravetch
openaire   +2 more sources

Fc Receptors

2005
Fc receptors for immunoglobulin A (IgA) have been recognized functionally for many years. The myeloid receptor, FcαRI, is the most thoroughly characterized. It is structurally related to the FcγRs and Fce{open}RI and also associates with the FcR γ chain dimer.
Woof, Jenny M., Van Egmond, Marjolein, Kerr, Michael A.   +2 more
openaire   +2 more sources