Results 211 to 220 of about 153,756 (258)
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Fc Receptor Homologs (FcRH1-5) Extend the Fc Receptor Family
2002Receptors for the Fc portion of immunoglobulins (FcR) are expressed broadly among cells of the immune system (Ravetch and Kinet 1991; Daeron 1997). The differential expression of these Ig isotope-specific receptors enable them to modulate cellular and humoral immunity by linking their antibody ligands with effector cells.
R S, Davis +3 more
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Clinical Immunology and Immunopathology, 1989
Considerable recent progress has been made in our understanding of how IgG immune complexes interact with plasma membrane Fc receptors (FcR) to mediate a diversity of biological responses in man. These responses include endocytosis of antibody complexes; stimulation of the secretion of various inflammatory mediators such as enzymes, oxygen products ...
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Considerable recent progress has been made in our understanding of how IgG immune complexes interact with plasma membrane Fc receptors (FcR) to mediate a diversity of biological responses in man. These responses include endocytosis of antibody complexes; stimulation of the secretion of various inflammatory mediators such as enzymes, oxygen products ...
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Annual Review of Immunology, 2007
Discovery of a large family of Fc receptor-like (FCRL) molecules, homologous to the well-known receptors for the Fc portion of immunoglobulin (FCR), has uncovered an impressive abundance of immunoglobulin superfamily (IgSF) genes in the human 1q21–23 chromosomal region and revealed significant diversity for these genes between humans and mice.
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Discovery of a large family of Fc receptor-like (FCRL) molecules, homologous to the well-known receptors for the Fc portion of immunoglobulin (FCR), has uncovered an impressive abundance of immunoglobulin superfamily (IgSF) genes in the human 1q21–23 chromosomal region and revealed significant diversity for these genes between humans and mice.
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Springer Seminars in Immunopathology, 2006
FcgammaRs are a family of heterogeneous molecules that play opposite roles in immune response and control the effector functions of IgG antibodies. In many cancers, IgG antibodies are produced that recognize cancer cells, form immune complexes and therefore, activate FcgammaR.
Lydie, Cassard +5 more
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FcgammaRs are a family of heterogeneous molecules that play opposite roles in immune response and control the effector functions of IgG antibodies. In many cancers, IgG antibodies are produced that recognize cancer cells, form immune complexes and therefore, activate FcgammaR.
Lydie, Cassard +5 more
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Annals of Hematology, 1998
IgG immune complexes are of central importance in the humoral immune system and strongly implicated in the pathogenesis of hematologic and rheumatic autoimmune disorders. Cross-linking of receptors for the Fc domain of IgG antibodies (FcgammaRs) triggers a wide variety of effector functions including phagocytosis, antibody-dependent cellular ...
J E, Gessner +3 more
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IgG immune complexes are of central importance in the humoral immune system and strongly implicated in the pathogenesis of hematologic and rheumatic autoimmune disorders. Cross-linking of receptors for the Fc domain of IgG antibodies (FcgammaRs) triggers a wide variety of effector functions including phagocytosis, antibody-dependent cellular ...
J E, Gessner +3 more
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2008
Antigen recognition by cells of the immune system occurs via many mechanisms. One important family of receptors involved in the recognition of immunoglobulin (Ig) coated particles and complexes are Fc receptors. Fc receptors recognize the Fc portion of Ig and are accordingly grouped into subfamilies. They are named depending upon which class of Ig they
Randall G. Worth, Alan D. Schreiber
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Antigen recognition by cells of the immune system occurs via many mechanisms. One important family of receptors involved in the recognition of immunoglobulin (Ig) coated particles and complexes are Fc receptors. Fc receptors recognize the Fc portion of Ig and are accordingly grouped into subfamilies. They are named depending upon which class of Ig they
Randall G. Worth, Alan D. Schreiber
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Current opinion in immunology, 1992
Advances in our understanding of the molecular structure of Fc receptors have been made at a rapid pace. Details of how Fc receptors are involved in cell triggering, e.g. allergic mediator release from mast cells, and IgE synthesis are also continuing to be elucidated, although much work is still required.
D H, Conrad +3 more
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Advances in our understanding of the molecular structure of Fc receptors have been made at a rapid pace. Details of how Fc receptors are involved in cell triggering, e.g. allergic mediator release from mast cells, and IgE synthesis are also continuing to be elucidated, although much work is still required.
D H, Conrad +3 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
1997
In the early 1970s, soon after the discovery of Fc receptors on lymphocytes, molecules binding antigen-complexed IgG were detected in culture supernatants of mouse activated T cells and called IgG-binding factors (IgG-BF). These IgG-BF were hypothesized to be derived from membrane FcγR and to correspond to soluble forms of these receptors.
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In the early 1970s, soon after the discovery of Fc receptors on lymphocytes, molecules binding antigen-complexed IgG were detected in culture supernatants of mouse activated T cells and called IgG-binding factors (IgG-BF). These IgG-BF were hypothesized to be derived from membrane FcγR and to correspond to soluble forms of these receptors.
openaire +1 more source