Results 101 to 110 of about 14,752 (202)

Infectious Triggers and Immune Dynamics in Guillain–Barré Syndrome: Revisiting Campylobacter jejuni and the Silent Role of Haemophilus influenzae

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Schematic representation of the gut‐brain axis and microbial triggers in Guillain–Barré Syndrome. Post‐infectious immune responses, particularly through molecular mimicry by pathogens, such as Campylobacter jejuni and Haemophilus influenzae, lead to demyelination and subsequent neuromuscular paralysis.
Aswathi Ramesh, Rajasekaran Subbarayan, Dhasarathdev Srinivasan, Ranjith Balakrishnan, Rupendra Shrestha, Ankush Chauhan   +5 more
wiley   +1 more source

The Effect of Anti‐3‐Hydroxy‐3‐Methylglutaryl‐CoA Reductase (HMGCR) Human Autoantibodies on Muscle Regeneration in Mice

Muscle &Nerve, Volume 72, Issue 6, Page 1300-1308, December 2025.
ABSTRACT Introduction/Aims Anti‐3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR) autoantibodies (aAbs) are pathogenic in immune‐mediated necrotizing myopathy (IMNM), partly through complement activation. C5 inhibition did not restore muscle strength in mice or patients with overt IMNM, suggesting additional pathogenic mechanisms.
Sarah Julien, Honorine Tomasevic, Thara Jaworski, Rachid Zoubairi, Jeremie Martinet, Laurent Drouot, Olivier Boyer   +6 more
wiley   +1 more source

Binding of therapeutic Fc-fused factor VIII to the neonatal Fc receptor at neutral pH associates with poor half-life extension

Haematologica
Fusion of therapeutic proteins to the Fc fragment of human IgG1 promotes their FcRn-mediated recycling and subsequent extension in circulating half-life.
Alejandra Reyes-Ruiz, Sandrine Delignat, Aishwarya Sudam Bhale, Victoria Daventure, Robin V. Lacombe, Leslie Dourthe, Olivier Christophe, Sune Justesen, Krishnan Venkataraman, Jordan D. Dimitrov, Sebastien Lacroix-Desmazes   +10 more
doaj   +1 more source

Functionalized FcRn-targeted nanosystems for oral drug delivery: A new approach to colorectal cancer treatment

, 2022
Fatima Hameedat, Nuria A. Pizarroso, Natália Teixeira, Soraia Pinto, Bruno Sarmento   +4 more
openalex   +1 more source

A szarvasmarha neonatalis Fc receptor (bFcRn) által mediált IgG katabolizmus és epithelialis transzport molekuláris szintű elemzése = Studies on the bovine FcRn mediated IgG catabolism and epithelial transport at molecular level [PDF]

, 2009
A pályázat révén jelentősen bővítettük a szarvasmarha FcRn (bFcRn) szerepéről alkotott ismereteinket arról hogyan szabályozza ez a receptor az IgG homeosztázisát.
Doleschall, Márton, Frenyó, Vilmos László, Jancsik, Veronika, Kacskovics, Imre, Kis, Zsuzsanna, Mayer, Balázs   +5 more
core  

Insight in the Unmet Needs Encountered During the Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Journal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired immune‐mediated disorder affecting peripheral nerves, manifesting most commonly as symmetric, proximal, and distal weakness with sensory loss. Although the 2021 European Academy of Neurology/Peripheral Nerve Society guidelines provide evidence‐based and ...
Jeffrey A. Allen, Helmar C. Lehmann, Eduardo Nobile‐Orazio, Luis Querol, Yusuf A. Rajabally   +4 more
wiley   +1 more source

Serum Autoantibody Lowering by the Anti-FcRn Monoclonal Antibody, Nipocalimab, Correlates With Clinical Improvement in Generalized Myasthenia Gravis Patients [PDF]

, 2022
Sindhu Ramchandren, Jeff Guptill, Carlo Antozzi, Vera Bril, Josep Gámez, Sven G. Meuth, Richard M. Nowak, Dianna Quan, Maria Teresa Sevilla Mantecon, Leona Ling, Yaowei Zhu, Keith Karcher, Hong Sun   +12 more
openalex   +1 more source

bFcRn transzgenikus juh előállítása = Generation of the bFcRn transgenic sheep [PDF]

, 2009
Munkacsoportunk (ELTE, Immunológiai Tsz) a szarvasmarha neonatalis Fc receptor (bFcRn) szerepét vizsgálja az IgG homeosztázisban (maternális immuntranszport, katabolizmus, humorális immunválasz).
Kacskovics, Imre
core  

Utility and Safety of Romiplostim in Pediatric Allogeneic Stem Cell Transplantation

Pediatric Transplantation, Volume 29, Issue 8, December 2025.
ABSTRACT Background The use of romiplostim, a thrombopoietin agonist, has increased in the last decade for the treatment of immune mediated thrombocytopenia and severe aplastic anemia. Its utility has been explored in the management of delayed platelet engraftment and secondary platelet failure during stem cell transplant (SCT), but its use has ...
Srividhya Senthil, Abdul Moothedath, Jane Elizabeth Potter, Heather Mcgrath Wilkinson, Eden Whiteside, Ramya Nataraj, Omima Mustafa, Claire Horgan, Denise Bonney, Sarah Brett, Rob Wynn   +10 more
wiley   +1 more source

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission [PDF]

, 2022
Weizhong Li, Tao Wang, Arunraj Mekhemadhom Rajendrakumar, Gyanada Acharya, Zizhen Miao, Berin P. Varghese, Hailiang Yu, Bibek Dhakal, Tanya LeRoith, Wenbin Tuo, Xiaoping Zhu   +10 more
openalex   +1 more source