Results 151 to 160 of about 15,564 (249)

Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin

, 2017
Célia Dechavanne, Sébastien Dechavanne, Ibrahim Sadissou, Adjimon Gatien Lokossou, Fernanda Alvarado, Magalie Dambrun, Kabirou Moutaïrou, David Courtin, Grégory Nuel, André Garcia, Florence Migot‐Nabias, Christopher L. King   +11 more
openalex   +2 more sources

pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling [PDF]

, 2014
M. Jack Borrok, Yanli Wu, Nurten Beyaz, Xiang‐Qing Yu, Vaheh Oganesyan, William F. Dall’Acqua, Ping Tsui   +6 more
openalex   +1 more source

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics [PDF]

, 2017
Nicole Piche‐Nicholas, Lindsay B. Avery, Amy King, Mania Kavosi, Mengmeng Wang, Denise M. O’Hara, Lioudmila Tchistiakova, Madan Katragadda   +7 more
openalex   +1 more source

Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules

, 2013
Andrew W. Weflen, Nina Baier, Qing-Juan Tang, Malon Van den Hof, Richard S. Blumberg, Wayne I. Lencer, Ramiro Massol   +6 more
openalex   +2 more sources

Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn) [PDF]

, 2006
William F. Dall’Acqua, Peter A. Kiener, Herren Wu   +2 more
openalex   +1 more source

Serum albumin and its interaction with the neonatal Fc receptor (FcRn) : characterization of the albumin/FcRn-binding mechanism

, 2013
In the past a lot of different biomolecular therapeutics were developed. A common problem using small molecules in therapy is their reduced serum concentration after short time period. The human body clears therapeutic molecules which have a size beneath the kidney clearance threshold in minutes to hours.
openaire   +2 more sources

Data from Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies

, 2023
Lidia Nazarova, Hanine Rafidi, Danielle Mandikian, Gregory Z. Ferl, James T. Koerber, C. Davies, Sheila Ulufatu, Jason Ho, Jeffrey Lau, Shang‐Fan Yu, James A. Ernst, Jack Sadowsky, C. Andrew Boswell   +12 more
openalex   +1 more source

Crucial Role for Immune Complexes but Not FcRn in Immunization against Anti–TNF-α Antibodies after a Single Injection in Mice [PDF]

, 2017
Christophe Arnoult, Guillaume Brachet, Diana Cadena Castaneda, Nicolas Azzopardi, Christophe Passot, Céline Desvignes, Gilles Paintaud, Nathalie Heuzé‐Vourc'h, Hervé Watier, Valérie Gouilleux‐Gruart   +9 more
openalex   +1 more source

Influence ofFCRNexpression on lung decline and intravenous immunoglobulin catabolism in common variable immunodeficiency patients [PDF]

, 2014
Jiří Litzman
openalex   +1 more source

Anti-FcRn Monoclonal Antibody SYNT001 [PDF]

, 2020
openaire   +1 more source