Results 161 to 170 of about 15,564 (249)

Optimizing human FcRn mouse models to improve pharmacokinetic evaluation of antibody drug candidates. [PDF]

MAbs
Christianson G, Howard ZM, Kenney S, Lowell E, Bethur N, Roopenian D, Gonzalo-Gil E.   +6 more
europepmc   +1 more source

FcRn Blockade as a Targeted Therapeutic Strategy in Antibody-Mediated Autoimmune Diseases: A Focus on Warm Autoimmune Hemolytic Anemia [PDF]

Michael Sandhu, Irina Murakhovskaya
openalex   +1 more source

Effects of the FcRn developmental pharmacology on the pharmacokinetics of therapeutic monoclonal IgG antibody in pediatric subjects using minimal physiologically-based pharmacokinetic modelling [PDF]

, 2018
Deni Hardiansyah, Chee M. Ng
openalex   +1 more source

Polypharmacology of S-1117, an Fc-fused IgG-selective degrading enzyme, for chronic treatment of autoantibody-mediated diseases. [PDF]

Proc Natl Acad Sci U S A
Sanmarco LM, Pellerin A, Green T, Plasencia A, Anderson JM, Le N, Newton A, Chen J, Ramello MC, Peckner R, Manasson J, Xing Y, Vital H, Higginson-Scott N, Sundy JS, Otipoby KL, Mascanfroni ID.   +16 more
europepmc   +1 more source

Case Report: KLHL11 encephalitis in a female patient with dual primary malignancies of breast and lung cancer: response to FcRn inhibitor therapy [PDF]

Yapeng Li, Haoran Xing, Zhentang Cao, Pan Cui, Lu Zhao   +4 more
openalex   +1 more source

Transplacental Antibody Transfer: Mechanisms, Pregnancy-Related Disruptions, and Emerging Experimental Models. [PDF]

Antibodies (Basel)
Li Q, Huang Z, Saeed Z, Greer O, Harker JA, Shah NM.   +5 more
europepmc   +1 more source

Table 2_Safety profile of complement C5 inhibitors and FcRn inhibitors in the treatment of myasthenia gravis: analysis of the FAERS database and disease-gene interaction network.docx

Luqiong Wang (22389295), Jiaojiao Chen (6711764), Huixiang Li (280714), Lin Wang (11986), Feiyu Liu (18291112), Xiaoli Jiang (418410)   +5 more
openalex   +1 more source

Vergleich von FcRn-Antagonismus und C5 Komplementinhibitionin generalisierter Myasthenia gravis

Niklas Huntemann, Lea Gerischer, Meret Herdick, Christopher Nelke, Frauke Stascheit, Sarah Hoffmann, Musa Öztürk, Christina B. Schroeter, Sophie Lehnerer, Martin T. Stein, Christine M. Schubert, Christiane Schneider‐Gold, Steffen Pfeuffer, Heidrun H Krämer-Best, Felix F. Konen, Thomas Skripuletz, Marc Pawlitzki, Stefanie Glaubitz, Jana Zschüntzsch, Valerie Scherwietes, Andreas Totzeck, Tim Hagenacker, Sven G. Meuth, Andreas Meisel, Tobias Ruck   +24 more
openalex   +2 more sources

Precision Immunomodulation in Pregnancy - Lessons from Nipocalimab. [PDF]

NEJM Evid
Eke AC.
europepmc   +1 more source

Elucidating the enigmatic biology of arteriviruses through receptor discovery. [PDF]

J Virol
Bailey AL.
europepmc   +1 more source