Results 151 to 160 of about 5,026 (198)

Successful Birth After First-Trimester Ravulizumab Exposure in a Patient With Paroxysmal Nocturnal Hemoglobinuria: A Case Report. [PDF]

open access: yesEJHaem
Morioka T   +12 more
europepmc   +1 more source

Antibody glycosylation in neuroimmune diseases. [PDF]

open access: yesJ Transl Med
Li K   +10 more
europepmc   +1 more source

Dulaglutide and pregnancy: a comprehensive safety assessment using the <i>ex vivo</i> placenta perfusion and <i>in vitro</i> models. [PDF]

open access: yesFront Pharmacol
Kuoni S   +5 more
europepmc   +1 more source

Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effects of FcRn Inhibitors in Mice, Rats, and Monkeys [PDF]

open access: yesJournal of Pharmaceutical Sciences, 2019
There is a growing interest in developing inhibitors of the neonatal Fc-receptor, FcRn, for use in the treatment for humoral autoimmune conditions. We have developed a new physiologically based pharmacokinetic model that is capable of characterizing the pharmacokinetics and pharmacodynamics of anti-FcRn monoclonal antibodies (mAb) in mice, rats, and ...
Joseph P Balthasar
exaly   +3 more sources

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