Results 151 to 160 of about 630,325 (166)
Targeting FcRn to Generate Antibody-Based Therapeutics
Trends in Pharmacological Sciences, 2018 The MHC class I-related receptor FcRn serves multiple roles ranging from the regulation of levels of IgG isotype antibodies and albumin throughout the body to the delivery of antigen into antigen loading compartments in specialized antigen-presenting ...
Raimund Ober, E Sally Ward
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The multiple facets of FcRn in immunity
Immunological Reviews, 2015 The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in various tissues, providing newborns with humoral immunity, and for prolonging the half-life of IgG.
Gestur Vidarsson
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Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
Proceedings of the National Academy of Sciences of the United States of America, 2017 The neonatal crystallizable fragment receptor (FcRn) is responsible for maintaining the long half-life and high levels of the two most abundant circulating proteins, albumin and IgG.
Wayne Lencer, Sanda Win, Kristi Baker
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Structure–activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction
Bioorganic and Medicinal Chemistry, 2008Adam R Mező
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The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy
Advanced Drug Delivery Reviews, 2015Jonathan Sockolosky, Francis C Szoka
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The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study
Science Translational Medicine, 2017Ian White +2 more
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