Transgenic inhibition of neuronal calcineurin activity in the forebrain facilitates fear conditioning, but inhibits the extinction of contextual fear memories [PDF]
, 2008 It is unclear whether protein phosphatases, which counteract the actions of protein kinases, play a beneficial role in the formation and extinction of previously acquired fear memories.
Eisel, Ulrich L. M. +4 more
core +8 more sources
Reversible plasticity of fear memory-encoding amygdala synaptic circuits even after fear memory consolidation. [PDF]
PLoS ONE, 2011 It is generally believed that after memory consolidation, memory-encoding synaptic circuits are persistently modified and become less plastic. This, however, may hinder the remaining capacity of information storage in a given neural circuit.
Ingie Hong +14 more
doaj +1 more source
Enhanced Instructed Fear Learning in Delusion-Proneness
Frontiers in Psychology, 2022 Psychosis is associated with distorted perceptions and deficient bottom-up learning such as classical fear conditioning. This has been interpreted as reflecting imprecise priors in low-level predictive coding systems. Paradoxically, overly strong beliefs,
Anaïs Louzolo +7 more
doaj +1 more source
Molecular Brain, 2019 Information from direct experience and observation of others is integrated in the brain to enable appropriate responses to environmental stimuli. Fear memory can be acquired by observing a conspecific’s distress.
Hiroshi Nomura +4 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2014 The formation of fear memory to a specific stimulus leads to subsequent fearful response to that stimulus. However, it is not known whether the formation of fear memory can affect other memories.
Gil eJoels, Raphael eLamprecht
doaj +1 more source
Who's afraid of the big bad wolf: a prospective paradigm to test Rachman's indirect pathways in children [PDF]
, 2001 Rachman's theory [The conditioning theory of fear insition: a critical examination. Behav. Res. Ther. 15 (1977) 375–387] of fear acquisition suggests that fears and phobias can be acquired through three pathways: direct conditioning, vicarious learning ...
Ajzen +56 more
core +1 more source
Avoidant symptoms in PTSD predict fear circuit activation during multimodal fear extinction [PDF]
, 2013 Convergent evidence suggests that individuals with posttraumatic stress disorder (PTSD) exhibit exaggerated avoidance behaviors as well as abnormalities in Pavlonian fear conditioning.
Israel eLiberzon +4 more
core +2 more sources
Contextual Fear Conditioning in Zebrafish [PDF]
Learning & Memory, 2016 AbstractZebrafish are a genetically tractable vertebrate that hold considerable promise for elucidating the molecular basis of behavior. Although numerous recent advances have been made in the ability to precisely manipulate the zebrafish genome, much less is known about many aspects learning and memory in adult fish. Here, we develop a contextual fear
Kenney, Justin W. +3 more
openaire +2 more sources
Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus
Frontiers in Cellular Neuroscience, 2019 Contextual fear conditioning is a Pavlovian conditioning paradigm capable of rapidly creating fear memories to contexts, such as rooms or chambers.
Nicholas Chaaya +19 more
doaj +1 more source
Generalization gradients for fear and disgust in human associative learning
Scientific Reports, 2021 Previous research indicates that excessive fear is a critical feature in anxiety disorders; however, recent studies suggest that disgust may also contribute to the etiology and maintenance of some anxiety disorders.
Jinxia Wang +4 more
doaj +1 more source