Results 41 to 50 of about 41,850 (262)

Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice

Scientific Reports, 2021
In this study we demonstrate that 2 month old APPswe/PS1dE9 mice, a transgenic model of Alzheimer’s disease, exhibited intact short-term memory in Pavlovian hippocampal—dependent contextual fear learning task. However, their long-term memory was impaired.
Smitha Karunakaran
doaj   +1 more source

Fear Conditioning to Subliminal Fear Relevant and Non Fear Relevant Stimuli

PLoS ONE, 2014
A growing body of evidence suggests that conscious visual awareness is not a prerequisite for human fear learning. For instance, humans can learn to be fearful of subliminal fear relevant images--images depicting stimuli thought to have been fear relevant in our evolutionary context, such as snakes, spiders, and angry human faces.
Lipp, Ottma V., Kempnich, Clare, Jee, Sang Hoon, Arnold, Derek H.   +3 more
openaire   +8 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Short-Term Total Sleep-Deprivation Impairs Contextual Fear Memory, and Contextual Fear-Conditioning Reduces REM Sleep in Moderately Anxious Swiss Mice

Frontiers in Behavioral Neuroscience, 2017
The conditioning tasks have been widely used to model fear and anxiety and to study their association with sleep. Many reports suggest that sleep plays a vital role in the consolidation of fear memory.
Munazah F. Qureshi, Sushil K. Jha
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Auditory fear memory retrieval requires BLA-LS and LS-VMH circuitries via GABAergic and dopaminergic neurons

EMBO Reports
Fear and associated learning and memory are critical for developing defensive behavior. Excessive fear and anxiety are important components of post-traumatic stress disorder.
Miao Chen, Jun Li, Weiran Shan, Jianjun Yang, Zhiyi Zuo   +4 more
doaj   +1 more source

Evaluating an internet-delivered fear conditioning and extinction protocol using response times and affective ratings

Scientific Reports, 2022
Pavlovian fear conditioning is widely used to study mechanisms of fear learning, but high-throughput studies are hampered by the labor-intensive nature of examining participants in the lab.
Johannes Björkstrand, Daniel S. Pine, Andreas Frick   +2 more
doaj   +1 more source

Adolescent Alcohol Exposure Results in Sex-specific Alterations in Conditioned Fear Learning and Memory in Adulthood

Frontiers in Pharmacology, 2022
The present study used auditory fear conditioning to assess the impact of repeated binge-like episodes of alcohol exposure during adolescence on conditioned fear in adulthood.
L. Judson Chandler, Dylan T. Vaughan, Justin T. Gass   +2 more
doaj   +1 more source

Don't fear 'fear conditioning'

Neuroscience and Biobehavioral Reviews, 2017
The so-called 'replicability crisis' has sparked methodological discussions in many areas of science in general, and in psychology in particular. This has led to recent endeavours to promote the transparency, rigour, and ultimately, replicability of research.
Lonsdorf, Tina B., Menz, Mareike M., Andreatta, Marta, Fullana, Miguel A., Golkar, Armita, Haaker, Jan, Heitland, Ivo, Hermann, Andrea, Kuhn, Manuel, Kruse, Onno, Meir Drexler, Shira, Meulders, Ann, Nees, Frauke, Pittig, Andre, Richter, Jan, Römer, Sonja, Shiban, Youssef, Schmitz, Anja, Straube, Benjamin, Vervliet, Bram, Wendt, Julia, Baas, Johanna M.P., Merz, Christian J.   +22 more
openaire   +2 more sources

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source