Results 41 to 50 of about 50,736 (309)

Working memory and fear conditioning [PDF]

Proceedings of the National Academy of Sciences, 2003
Previous studies of associative learning implicate higher-level cognitive processes in some forms of classical conditioning. An ongoing debate is concerned with the extent to which attention and awareness are necessary for trace but not delay eye-blink conditioning [Clark, R. E. & Squire, L. R.
Carter, Ronald McKell, Hofstötter, Constanze, Tsuchiya, Naotsugu, Koch, Christof   +3 more
openaire   +3 more sources

Human fear conditioning: From neuroscience to the clinic [PDF]

Behaviour Research and Therapy, 2020
Both clinicians and neuroscientists have been long interested in the topic of fear conditioning, with recent advances in neuroscience, in particular, igniting a shared interest in further translation between these domains. Here, we review some historical aspects of this relationship and the progress that has been made in translating the neuroscientific
Fullana, M A, Dunsmoor, J E, Schruers, K R J, Savage, H S, Bach, D R, Harrison, B J   +5 more
openaire   +5 more sources

Deficiency of the RIβ subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats [PDF]

, 2021
The RIβ subunit of cAMP-dependent protein kinase (PKA), encoded by Prkar1b, is a neuronal isoform of the type I regulatory subunit of PKA. Mice lacking the RIβ subunit exhibit normal long-term potentiation (LTP) in the Schaffer collateral pathway of the ...
Kaneko, Takehito, Kuramoto, Takashi, Hirata, Yoshiki, Asano, Masahide, Hoang Trung, Hieu, Hayashida, Katsumi, Mori, Yasuo, Hieu, Hoang Trung, Kuwamura, Mitsuru, Yoshihara, Toru, Shirasuna, Koumei, Nakagawa, Yuki, Nakao, Akito   +12 more
core   +1 more source

Conditioned Fear Associated Phenotypes as Robust, Translational Indices of Trauma-, Stressor-, and Anxiety-related Behaviors

Frontiers in Psychiatry, 2014
Posttraumatic stress disorder (PTSD) is a heterogeneous disorder that affects individuals exposed to trauma (e.g., combat, interpersonal violence, and natural disasters).
Maria Anne Briscione, Tanja eJovanovic, Seth Davin Norrholm   +2 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Trace Fear Conditioning in Mice [PDF]

Journal of Visualized Experiments, 2014
In this experiment we present a technique to measure learning and memory. In the trace fear conditioning protocol presented here there are five pairings between a neutral stimulus and an unconditioned stimulus. There is a 20 sec trace period that separates each conditioning trial.
Joaquin N, Lugo, Gregory D, Smith, Andrew J, Holley   +2 more
openaire   +2 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Learning and nicotine interact to increase CREB phosphorylation at the jnk1 promoter in the hippocampus

, 2012
Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs).
Rachel L Poole, Gould, Thomas J., Michael D Adoff, Gould Thomas J., Kenney, Justin W., Thomas J Gould, Poole Rachel L., Poole, Rachel L., Logue, Sheree F., Kenney Justin W., Justin W Kenney, Sheree F Logue, Logue Sheree F., Adoff, Michael D., Adoff Michael D.   +14 more
core   +1 more source

Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

eLife, 2018
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning.
Ran Inoue, Kareem Abdou, Ayumi Hayashi-Tanaka, Shin-ichi Muramatsu, Kaori Mino, Kaoru Inokuchi, Hisashi Mori   +6 more
doaj   +1 more source