Results 21 to 30 of about 19,755 (259)
Frontiers in Behavioral Neuroscience, 2014 The formation of fear memory to a specific stimulus leads to subsequent fearful response to that stimulus. However, it is not known whether the formation of fear memory can affect other memories.
Gil eJoels, Raphael eLamprecht
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Amygdala depotentiation and fear extinction [PDF]
Proceedings of the National Academy of Sciences, 2007 Auditory fear memory is thought to be maintained by fear conditioning-induced potentiation of synaptic efficacy, which involves enhanced expression of surface AMPA receptor (AMPAR) at excitatory synapses in the lateral amygdala (LA). Depotentiation, reversal of conditioning-induced potentiation, has been proposed as a cellular mechanism ...
Jeongyeon, Kim +15 more
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Amygdala-ventral striatum circuit activation decreases long-term fear
eLife, 2016 In humans, activation of the ventral striatum, a region associated with reward processing, is associated with the extinction of fear, a goal in the treatment of fear-related disorders.
Susana S Correia +4 more
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Systemic Cellular Activation Mapping of an Extinction-Impaired Animal Model
Frontiers in Cellular Neuroscience, 2019 Fear extinction diminishes conditioned fear responses and impaired fear extinction has been reported to be related to anxiety disorders such as post-traumatic stress disorder (PTSD).
Kwanghoon Park, ChiHye Chung
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Running from fear: Exercise modulation of fear extinction [PDF]
Neurobiology of Learning and Memory, 2018 Extinction-based exposure therapy is the most common behavioral therapy for anxiety and trauma-related disorders, but fear tends to resurface even after successful extinction. Identification of novel strategies to enhance fear extinction and reduce fear relapse is of paramount importance to mental health. Exercise can enhance cognitive function, but it
Margaret K, Tanner +3 more
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Orexin A Differentially Influences the Extinction Retention of Recent and Remote Fear Memory
Frontiers in Neuroscience, 2018 Recently the role of the orexin system in the learning and memory, especially orexin A, which could enhance fear memory through regulating the activity of amygdala, has drawn considerable attention.
Le Shi +15 more
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Spontaneous recovery of fear reverses extinction-induced excitability of infralimbic neurons.
PLoS ONE, 2014 In rodents, the infralimbic (IL) region of the medial prefrontal cortex plays a key role in the recall of fear extinction. Previously we showed that fear conditioning decreases the intrinsic excitability of IL neurons, and that fear extinction reverses ...
Emmanuel Cruz +2 more
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Theta coupling within the medial prefrontal cortex regulates fear extinction and renewal
iScience, 2022 Summary: Fear learning, and its extinction, are fundamental learning processes that allow for a response adaptation to aversive events and threats in the environment.
Cong Wang +3 more
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Individual Differences in Conditioned Fear and Extinction in Female Rats
Frontiers in Behavioral Neuroscience, 2021 The inability to extinguish a traumatic memory is a key aspect of post-traumatic stress disorder (PTSD). While PTSD affects 10–20% of individuals who experience a trauma, women are particularly susceptible to developing the disorder. Despite this notable
Sarah C. Tryon +5 more
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Neural Plasticity, 2016 Vagus nerve stimulation (VNS) enhances the consolidation of extinction of conditioned fear. High frequency stimulation of the infralimbic cortex (IL) produces long-term potentiation in the basolateral amygdala (BLA) in rats given VNS-paired extinction ...
Amanda C. Alvarez-Dieppa +3 more
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