Results 31 to 40 of about 637,566 (254)
Individual Differences in Conditioned Fear and Extinction in Female Rats
Frontiers in Behavioral Neuroscience, 2021 The inability to extinguish a traumatic memory is a key aspect of post-traumatic stress disorder (PTSD). While PTSD affects 10–20% of individuals who experience a trauma, women are particularly susceptible to developing the disorder. Despite this notable
Sarah C. Tryon +5 more
doaj +1 more source
Neural Plasticity, 2016 Vagus nerve stimulation (VNS) enhances the consolidation of extinction of conditioned fear. High frequency stimulation of the infralimbic cortex (IL) produces long-term potentiation in the basolateral amygdala (BLA) in rats given VNS-paired extinction ...
Amanda C. Alvarez-Dieppa +3 more
doaj +1 more source
Social Company by a Receptive Mating Partner Facilitates Fear Extinction
Frontiers in Neuroscience, 2020 Fear extinction remains an unresolved challenge for behavioral exposure therapy in patients with post-traumatic stress disorder (PTSD). Previous reports have suggested that social support from either familiar or unfamiliar same-sex partners is beneficial
Feng Gao +12 more
doaj +1 more source
Exposure to Violence and Neglect Images Differentially Influences Fear Learning and Extinction
, 2020 The mechanisms by which exposure to adversity contributes to psychopathology development are poorly understood. Recent models link experiences of threat of harm and deprivation to psychopathology via disruptions in learning mechanisms underlying fear ...
Waters, Allison M +2 more
core +1 more source
Berberine Facilitates Extinction and Prevents the Return of Fear
Frontiers in Pharmacology, 2022 Exposure to a catastrophic event or intense stimulation can trigger fear memories, and the threatening memories persist even over a lifetime. Exposure therapy is based on extinction learning and is widely used to treat fear-related disorders, but its ...
Shihao Huang +9 more
doaj +1 more source
Dissecting the role of defined neuronal populations in fear learning [PDF]
, 2014 The astonishing plasticity of the brain and its ability for continuous learning and memory formation are among its most essential functions, since constant adaptation to the environment is critical for an animal’s survival.
Eggert Wolff, Steffen Benjamin
core +1 more source
Fear extinction learning modulates large-scale brain connectivity
NeuroImage, 2021 Exploring the neural circuits of the extinction of conditioned fear is critical to advance our understanding of fear- and anxiety-related disorders. The field has focused on examining the role of various regions of the medial prefrontal cortex, insular ...
Zhenfu Wen +2 more
doaj +1 more source
Basic and Clinical Neuroscience, 2022 Introduction: The basolateral amygdala (BLA) and infralimbic area (IL) of the medial prefrontal cortex (mPFC) are two interconnected brain structures that mediate both fear memory expression and extinction.
Abbas Ali Vafaei +4 more
doaj
Neurobiology of Stress, 2021 Impaired extinction of conditioned fear is associated with anxiety disorders. Common lifestyle factors, like isolation stress and exercise, may alter the ability to extinguish fear. However, the effect of and interplay between these factors on adolescent
Katherine D. Drummond +5 more
doaj +1 more source
The effects of the benzodiazepine, midazolam, on extinction and re-extinction of conditioned fear [PDF]
, 2012 Extinction of Pavlovian conditioned fear requires activation of the basolateral amygdala (BLA). Concurrent with this activation, effective long-term extinction requires animals to be able to express and actively inhibit their fear across the course of ...
Hart, Genevra
core +1 more source