Results 41 to 50 of about 19,755 (259)
Frontiers in Behavioral Neuroscience, 2015 Context plays a central role in retrieving (fear) memories. Accordingly, context manipulations are inherent to most return of fear (ROF) paradigms (in particular renewal), involving contextual changes after fear extinction.
Rachel eSjouwerman +2 more
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Frontiers in Global Women's Health, 2021 Reproductive experience leads to long-lasting changes in anxiety-like behaviour and fear extinction, the laboratory model of exposure therapy for anxiety disorders.
Jodie E. Pestana +4 more
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Sex differences in fear extinction
Neuroscience & Biobehavioral Reviews, 2019 Despite the exponential increase in fear research during the last years, few studies have included female subjects in their design. The need to include females arises from the knowledge gap of mechanistic processes underlying the behavioral and neural differences observed in fear extinction.
E.R. Velasco +3 more
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IGF-1 facilitates extinction of conditioned fear [PDF]
eLife, 2020 SUMMARYInsulin-like growth factor-1 (IGF-1) plays a key role in synaptic plasticity, degenerative diseases, spatial learning, and anxiety-like behavioral processes. While IGF-1 regulates neuronal activity in many areas of the brain, its effect on synaptic plasticity and animal behavior dependent on the prefrontal cortex remain unexplored. Here, we show
Laura E Maglio +6 more
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Scientific Reports, 2021 The balance between activities of fear neurons and extinction neurons in the basolateral nucleus of the basal amygdala (BAL) has been hypothesized to encode fear states after extinction.
Junghwa Lee, Bobae An, Sukwoo Choi
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Extinction of Fear Memory Attenuates Conditioned Cardiovascular Fear Reactivity [PDF]
Frontiers in Behavioral Neuroscience, 2018 Post-traumatic stress disorder (PTSD) is characterized by a heightened emotional and physiological state and an impaired ability to suppress or extinguish traumatic fear memories. Exaggerated physiological responses may contribute to increased cardiovascular disease (CVD) risk in this population, but whether treatment for PTSD can offset CVD risk ...
Adam P. Swiercz +4 more
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Frontiers in Behavioral Neuroscience, 2017 The amygdala, a critical structure for both Pavlovian fear conditioning and fear extinction, receives sparse but comprehensive dopamine innervation and contains dopamine D1 and D2 receptors.
Yan-Wei Shi +10 more
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Recent fear is resistant to extinction [PDF]
Proceedings of the National Academy of Sciences, 2006 In some individuals, fearful experiences (e.g., combat) yield persistent and debilitating psychological disturbances, including posttraumatic stress disorder (PTSD). Early intervention (e.g., debriefing) after psychological trauma is widely practiced and argued to be an effective strategy for limiting subsequent psychopathology, although ...
Maren, Stephen, Chang, Chun-hui
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Utilizing rewards to dampen fear and its recovery
Scientific ReportsFearful memories can be extinguished by repeated exposure, without aversive outcomes. Fear extinction as the basis for exposure therapy, is a common treatment for anxiety and fear-related disorders, but it can be unpleasant and does not always work.
Elliot C. Brown +4 more
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Amphetamine and extinction of cued fear [PDF]
Neuroscience Letters, 2010 Much research is focused on developing novel drugs to improve memory. In particular, psychostimulants have been shown to enhance memory and have a long history of safe use in humans. In prior work, we have shown that very low doses of amphetamine administered before training on a Pavlovian fear-conditioning task can dramatically facilitate the ...
Stephanie A, Carmack +2 more
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