Results 61 to 70 of about 637,566 (254)

A NMDA receptor antagonist, MK-801 impairs consolidating extinction of auditory conditioned fear responses in a Pavlovian model. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND: In auditory fear conditioning, repeated presentation of the tone in the absence of shock leads to extinction of the acquired fear responses.
Jun-Li Liu   +7 more
doaj   +1 more source

Identification of the Similarities and Differences of Molecular Networks Associated With Fear Memory Formation, Extinction, and Updating in the Amygdala

open access: yesFrontiers in Molecular Neuroscience, 2021
Abnormality of fear memory is one of the important pathogenic factors leading to post-traumatic stress disorder (PTSD), anxiety disorder, and other mental disorders.
Jinfeng Su   +10 more
doaj   +1 more source

The renewal of extinguished conditioned fear with fear-relevant and fear-irrelevant stimuli by a context change after extinction [PDF]

open access: yes, 2008
The acquisition, extinction, and subsequent recovery of conditioned fear can be influenced by the nature of the conditional stimulus (CS) and the context in which the CS is presented.
Longbottom, Paula L, Neumann, David L
core   +1 more source

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

open access: yesAdvanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song   +8 more
wiley   +1 more source

Carbon dioxide reactivity predicts fear expression after extinction and retrieval-extinction in rats

open access: yes, 2023
Cues present during a traumatic event may result in maladaptive fear responses. These responses can be attenuated through extinction learning, which is a core component of exposure therapy. Exposure/extinction is effective for some, but not all.
Monfils, Marie, Raskin, Marissa
core   +1 more source

Inverse Design of Nanoparticulate Materials

open access: yesAdvanced Materials, EarlyView.
Inverse design shifts nanomaterial development from empirical trial‐and‐error to predictive model‐driven strategies. It can rely on knowledge‐based, data‐based, or hybrid process and property functions. This perspective article provides a practical framework for applying inverse design based on instructive examples. It discusses which modeling approach
Nabi Etienne Traoré   +5 more
wiley   +1 more source

Neuronal circuits of fear extinction

open access: yes, 2010
Fear extinction is a form of inhibitory learning that allows for the adaptive control of conditioned fear responses. Although fear extinction is an active learning process that eventually leads to the formation of a consolidated extinction memory, it is ...
Singewald N.   +11 more
core   +1 more source

Photoluminescence Reshaping via Structural Confinement and Local Density of Optical States Control in Ir(III)‐Doped Biodegradable Metasurfaces

open access: yesAdvanced Materials Technologies, EarlyView.
Phosphorescent biodegradable metasurface showing vibronic selection and spectral photoluminescence narrowing. Anti‐correlation between experimental LDOS and measured lifetimes. ABSTRACT Metasurfaces incorporating phosphorescent emitters offer a route to engineer radiative and vibronic processes beyond chemical design.
Vincenzo Caligiuri   +11 more
wiley   +1 more source

Directional theta coherence in prefrontal cortical to amygdalo-hippocampal pathways signals fear extinction. [PDF]

open access: yesPLoS ONE, 2013
Theta oscillations are considered crucial mechanisms in neuronal communication across brain areas, required for consolidation and retrieval of fear memories.
Jörg Lesting   +5 more
doaj   +1 more source

Erasing Fear Memories with Extinction Training: Figure 1.

open access: yes, 2010
Decades of behavioral studies have confirmed that extinction does not erase classically conditioned fear memories. For this reason, research efforts have focused on the mechanisms underlying the development of extinction-induced inhibition within fear ...
Marie H. Monfils   +6 more
core   +1 more source

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