Results 31 to 40 of about 7,060,917 (288)

The Influence of Serotonin on Fear Learning

PLoS ONE, 2012
Learning of associations between aversive stimuli and predictive cues is the basis of Pavlovian fear conditioning and is driven by a mismatch between expectation and outcome. To investigate whether serotonin modulates the formation of such aversive cue-outcome associations, we used functional magnetic resonance imaging (fMRI) and dietary tryptophan ...
Catherine Hindi Attar, Barbara Finckh, Christian Büchel   +2 more
openaire   +4 more sources

Appetitive behavioral traits and stimulus intensity influence maintenance of conditioned fear

Frontiers in Behavioral Neuroscience, 2013
Individual differences in appetitive learning have long been reported, and generally divide into two classes of responses: cue- vs. reward-directed. The influence of cue- vs. reward-directed phenotypes on aversive cue processing, is less well understood.
Megan eOlshavsky, Carolyn E. Jones, Hongjoo J Lee, Marie H Monfils   +3 more
doaj   +1 more source

Smokers show increased fear responses towards safety signals during fear generalization, independent from acute smoking

Scientific Reports, 2022
Smoking is highly prevalent among patients with anxiety disorders. Previous studies suggest that smokers show altered fear learning as compared to non-smokers.
Madeleine Mueller, Smilla Weisser, Jonas Rauh, Jan Haaker   +3 more
doaj   +1 more source

Olfactory Bulb Muscarinic Acetylcholine Type 1 Receptors Are Required for Acquisition of Olfactory Fear Learning

Frontiers in Behavioral Neuroscience, 2019
The olfactory bulb (OB) receives significant cholinergic innervation and widely expresses cholinergic receptors. While acetylcholine (ACh) is essential for olfactory learning, the exact mechanisms by which ACh modulates olfactory learning and whether it ...
Jordan M. Ross, Mounir Bendahmane, Max L. Fletcher   +2 more
doaj   +1 more source

Modulation of the extinction of fear learning

Brain Research Bulletin, 2014
We review recent work on extinction learning with emphasis on its modulation. Extinction is the learned inhibition of responding to previously acquired tasks. Like other forms of learning, it can be modulated by a variety of neurotransmitter systems and behavioral procedures.
Jociane C, Myskiw, Ivan, Izquierdo, Cristiane R G, Furini   +2 more
openaire   +2 more sources

Fear conditioning- and extinction-induced neuronal plasticity in the mouse amygdala [PDF]

, 2009
Experience-dependent changes in behavior are mediated by long-term functional modifications in brain circuits. To study the underlying mechanisms, our lab is using classical auditory fear conditioning, a simple and robust form of associative learning. In
Ciocchi, Stéphane
core   +1 more source

Auditory associative learning drives synaptic responses in tail of the striatum spiny projection neurons

iScience
Summary: The association of cues with the absence or presence of danger is crucial to survival. The synaptic changes that enable association with the absence of danger are unknown, but a role for the tail of the striatum (TS) has been implicated.
Adrien Stanley, Se Joon Choi, Anika Frank, Emily Makowicz, Stefano Cataldi, N. Shashaank, Eugene V. Mosharov, Clay Lacefield, Maria Concetta Miniaci, David Sulzer   +9 more
doaj   +1 more source

Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity

Frontiers in Neuroscience, 2019
Brain serotonin (5-hydroxytryptamine, 5-HT) system dysfunction is implicated in exaggerated fear responses triggering various anxiety-, stress-, and trauma-related disorders. However, the underlying mechanisms are not well understood.
Jonas Waider, Sandy Popp, Boris Mlinar, Alberto Montalbano, Francesco Bonfiglio, Benjamin Aboagye, Elisabeth Thuy, Raphael Kern, Christopher Thiel, Naozumi Araragi, Naozumi Araragi, Evgeniy Svirin, Evgeniy Svirin, Angelika G. Schmitt-Böhrer, Renato Corradetti, Christopher A. Lowry, Klaus-Peter Lesch, Klaus-Peter Lesch, Klaus-Peter Lesch   +18 more
doaj   +1 more source

Theta coupling within the medial prefrontal cortex regulates fear extinction and renewal

iScience, 2022
Summary: Fear learning, and its extinction, are fundamental learning processes that allow for a response adaptation to aversive events and threats in the environment.
Cong Wang, Peter G. Stratton, Pankaj Sah, Roger Marek   +3 more
doaj   +1 more source

Updating appetitive memory during reconsolidation window: critical role of cue-directed behavior and amygdala central nucleus.

Frontiers in Behavioral Neuroscience, 2013
When presented with a light cue followed by food, some rats simply approach the foodcup (Nonorienters), while others first orient to the light in addition to displaying the food-cup approach behavior (Orienters).
Megan E Olshavsky, Bryan eSong, Daniel J Powell, Carolyn E Jones, Marie H Monfils, Marie H Monfils, Hongjoo Joanne Lee   +6 more
doaj   +1 more source