Results 51 to 60 of about 167,189 (259)

I'M AWARE OF MY GOAL ORIENTATION, MY FEAR OF FAILURE WILL DECREASE!: THE EFFECT OF LEARNING AWARENESS RELATED TO GOAL ORIENTATION ON FEAR OF FAILURE

Jurnal Nalar Pendidikan, 2023
The problem that still occurs today is the fear of failure among students. This research aims to examine the effect of learning awareness related to goal orientation on fear of failure.
Helga Graciani Hidajat, Resi Shaumia Ratu Eka Permata, Retno Sulistiyaningsih, Flavia Aurelia Hidajat   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

3,4-Methylenedioxymethamphetamine facilitates fear extinction learning [PDF]

Translational Psychiatry, 2015
AbstractAcutely administered 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) has been proposed to have long-term positive effects on post-traumatic stress disorder (PTSD) symptoms when combined with psychotherapy. No preclinical data support a mechanistic basis for these claims.
Young, M B, Andero, R, Ressler, K J, Howell, L L   +3 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Molecular diversity and functional dynamics in the central amygdala

Frontiers in Molecular Neuroscience
The central amygdala (CeA) is crucial in integrating sensory and associative information to mediate adaptive responses to emotional stimuli. Recent advances in genetic techniques like optogenetics and chemogenetics have deepened our understanding of ...
Li-Feng Yeh, Shuzhen Zuo, Shuzhen Zuo, Pin-Wu Liu, Pin-Wu Liu   +4 more
doaj   +1 more source

Genetic influences on central and peripheral nervous system activity during fear conditioning

Translational Psychiatry, 2022
Fear conditioning is an evolutionarily conserved type of learning serving as a model for the acquisition of situationally induced anxiety. Brain function supporting fear conditioning may be genetically influenced, which in part could explain genetic ...
G. Kastrati, J. Rosén, M. Fredrikson, X. Chen, R. Kuja-Halkola, H. Larsson, K. B. Jensen, F. Åhs   +7 more
doaj   +1 more source

Unrelenting Fear Under Stress: Neural Circuits and Mechanisms for the Immediate Extinction Deficit

Frontiers in Systems Neuroscience, 2022
Therapeutic interventions for disorders of fear and anxiety rely on behavioral approaches that reduce pathological fear memories. For example, learning that threat-predictive stimuli are no longer associated with aversive outcomes is central to the ...
Stephen Maren
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Measuring fear: Association among different measures of fear learning.

Journal of Behavior Therapy and Experimental Psychiatry, 2021
Fear conditioning paradigms use various measures to assess learned fear, including autonomic arousal responses like skin conductance, and self-reports of both associative (US-expectancies) and evaluative (affective ratings) learning. The present study uses a dimensional approach to examine associations among fear indices directly.Seventy-three ...
Constantinou, Elena, Purves, Kirstin L., McGregor, Thomas, Lester, Kathryn J., Barry, Tom J., Treanor, Michael, Craske, Michelle G., Eley, Thalia C.   +7 more
openaire   +2 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source