Results 81 to 90 of about 213,674 (281)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Anxiety in synucleinopathies: neuronal circuitry, underlying pathomechanisms and current therapeutic strategies

npj Parkinson's Disease, 2023
Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein (αSyn) accumulation in neurons or glial cells, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Thuy Thi Lai, Birthe Gericke, Malte Feja, Michael Conoscenti, Moriel Zelikowsky, Franziska Richter   +5 more
doaj   +1 more source

Psychological Factors and Treatment Adherence Behavior in Patients With Chronic Heart Failure [PDF]

, 2007
Background: Chronic heart failure adversely affects 300,000 Australians. Symptom stabilization and prognosis are partially determined by patients following medical and lifestyle recommendations.
Dwyer, Jonathan, Head, Kathryn, Schweitzer, Robert   +2 more
core   +2 more sources

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Chronic non-specific low back pain - sub-groups or a single mechanism? [PDF]

, 2008
Copyright 2008 Wand and O'Connell; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
A Antal, A Antal, A Delitto, A Keller, A Moore, A Pascual-Leone, A Radebold, A Radebold, A Rosner, A Schrag, AF Bendix, AF Mannion, AF Molsberger, AH McGregor, AJ Harris, AV Apkarian, AV Apkarian, AWM Evers, B Kainz, B Schweikert, Benedict Martin Wand, BF Walker, BW Koes, BW Koes, C Eccleston, C Larivie're, C Leboeuf-Yde, C Leboeuf-Yde, C Maihöfner, C Maihöfner, C Richardson, C Schmahl, C Young-Casey, CJ Hsieh, CJ Lamoth, CJ Main, CJ Main, CJ McCarthy, CJ McCarthy, CPN Watson, CS McCabe, CS McCabe, D Turk, DA Seminowicz, DC Turk, DG Wilder, DI Cook, DJ Clauw, DJ Critchley, DL Riddle, DM Small, EE Bostan, EH Kääpä, EI Skargren, EJ Carragee, EJ Carragee, EL Hurwitz, EL Hurwitz, EM Hay, EM Wassermann, F Fregni, F Keefe, F Kleinstück, FJ Keefe, G Bronfort, G Jull, G Waddell, GA Koumantakis, GE Bekkering, GE Hicks, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GR Fink, H Flor, H Flor, H Flor, H Flor, H Flor, H Flor, H Frost, H Merskey, HJM Van Den Hoogen, ID Grachev, ID Grachev, ID Grachev, J Lorenz, J McCarthy, J Pells, JA Hayden, JA Hayden, JD Childs, JE Cassisi, JG Klein, JH Van Dieën, JL Carr, JL Porter, JM Fritz, JM Whitman, JS Lewis, JWS Vlaeyen, JWS Vlaeyen, KJ Petrie, KP Barr, KP Gill, L Klenerman, L Niemistö, L Vogt, LA Smith, LHM Pengel, LM McCracken, LM Smedstad, M Adams, M Jeannerod, M Leeuw, M Riipinen, M Van Der Hulst, M Van Tulder, M Yeh, MA Rogers, MC Cairns, MD Freeman, MD Grabiner, ME Geisser, MIV Mientjes, MN Baliki, MR Underwood, MS George, MW van Tulder, MW van Tulder, N Bogduk, N Bogduk, N Jousset, N Maniadakis, N Nies, Neil Edward O'Connell, NJ Zimny, NW Mok, P Dolan, P Jellema, P Kent, P Michaelson, P O'Sullivan, PB Fitzgerald, PB O'Sullivan, PB O'Sullivan, PH Canter, PH Ferreira, PJ Siddall, PJ Watson, PM Kent, R Andenaes, R Herbert, R Waxman, RA Deyo, RA McKenzie, RC de Charms, RJEM Smeets, RW Ostelo, RW Selles, S Brumagne, S Luoto, S Luoto, S Luoto, S Taimela, S Taimela, S Thompson, S Yusuf, SA Ferguson, SJ Linton, SJ Linton, SM Ott, T Bendix, T Flynn, T Giesecke, T Giesecke, T Honda, T Hyphantis, T Petersen, T Peterson, T Pincus, T Pincus, T Schmidt-Wilcke, The UK BEAM Trial Team, TS Carey, TZ Kincses, V Leinonen, VS Ramachandran, W Dankaerts, WJJ Assendelft, WO Spitzer, WS Marras, WS Marras, WS Marras, WS Marras, WS Marras   +198 more
core   +4 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Treatment of cardiomyopathy with PAP therapy in a patient with severe obstructive sleep apnea. [PDF]

, 2012
Obstructive sleep apnea is common in patients with heart failure. This case illustrates that treatment with PAP therapy can improve cardiac function in patients with both conditions.
Grewal, MD, Ritu G.
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Correlation between fear of disease progress and post⁃traumatic stress disorder among patients with acute myocardial infarction

Huli yanjiu, 2020
ObjectivesTo investigate the prevalence status of post traumatic stress disorder(PTSD) symptoms among patients with PTSD,and to explore the relationship between fear of disease progress and PTSD symptoms.MethodsA total of 256 patients with acute ...
ZENG Kai, CHEN Xiaofang, TU Yan, TENG Zhonghua, ZHOU Kexiong, ZHANG Lili   +5 more
doaj