Results 81 to 90 of about 483,021 (202)
Advanced Science, Volume 13, Issue 50, 7 September 2026.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
Fear Potentiated Startle and the Effects of Losartan on Extinction Learning
, 2019 Background – PTSD is a chronic and debilitating mental illness with limited available treatments. New medications, including Angiotensin Type 1 Receptor inhibitors, have been found to improve extinction learning retention in rodents and could be a means ...
Seidenberg, Jessica
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Impaired Synaptic Plasticity in a Rodent Model of Intimate Partner Violence‐Related Brain Injury
Hippocampus, Volume 36, Issue 5, September 2026.ABSTRACT Intimate partner violence‐related brain injury (IPV‐BI) predominantly affects women and often reflects both structural trauma from mild traumatic brain injury (mTBI), as well as ischemia/hypoxia from non‐fatal strangulation (NFS). This polytrauma can impair cognitive function, particularly learning and memory processes, which may contribute to
Justin Brand +8 more
wiley +1 more source
Fear-Potentiated Startle Paradigm in Mice
, 2012 Faculty adviser: Prof. Jonathan GewirtzTUF1 is a novel neuropeptide highly concentrated in the amygdala, hippocampus, hypothalamus, and the endocrine tissue.
Demova, Jiva, Zimbel, Max
core
CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues.
, 2009 Corticotropin-releasing factor (CRF) peptides and their receptors have crucial roles in behavioral and endocrine responses to stress. Dysregulation of CRF signaling has been linked to post-traumatic stress disorder, which is associated with increased ...
Holsboer, F. +6 more
core +1 more source
, 2003 The present thesis explored the neurobiological basis of three aspects of defense behaviors in humans. Positron emission tomography methodology was used, and changes in regional cerebral blood flow (rCBF) were measured as an index of neural activity ...
Rauch, Scott, +2 more
core +4 more sources
Social Fear Conditioning Paradigm in Virtual Reality: Social vs. Electrical Aversive Conditioning
Frontiers in Psychology, 2017 In a previous study we could show that social fear can be induced and extinguished using virtual reality (VR). In the present study, we aimed to investigate the belongingness effect in an operant social fear conditioning (SFC) paradigm which consisted of
Jonas Reichenberger +4 more
doaj +1 more source
, 1997 The amplitude of the acoustic startle response is reliably enhanced when elicited in the presence of bright light (light-enhanced startle) or in the presence of cues previously paired with shock (fear-potentiated startle).
Michael Davis, David L. Walker
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Excitotoxic lesions in the central nucleus of the amygdala attenuate stress-induced anxiety behavior
Frontiers in Behavioral Neuroscience, 2013 The extended amygdala, composed by the amygdaloid nuclei and the bed nucleus of the stria terminalis (BNST), plays a critical role in anxiety behavior.
Ana Paula eVentura-Silva +13 more
doaj +1 more source
Fear-Conditioning to Unpredictable Threats Reveals Sex and Strain Differences in Rat Fear-Potentiated Startle (FPS). [PDF]
Neuroscience, 2023 Olivera-Pasilio V, Dabrowska J.
europepmc +1 more source