Results 81 to 90 of about 1,866,866 (289)

‘ThinkCancer!’: randomised feasibility trial of a novel practice-based early cancer diagnosis intervention

BJGP Open
Background: UK cancer deaths remain high; primary care is key for earlier cancer diagnosis as half of avoidable delays occur here. Improvement is possible through lower referral thresholds, better guideline adherence, and better safety-netting systems ...
Stefanie LJ Disbeschl, Annie K Hendry, Alun Surgey, Daniel Walker, Nia Goulden, Bethany F Anthony, Richard Neal, Nefyn H Williams, Zoë Susannah Jane Hoare, Julia Hiscock, Rhiannon Tudor (RT) Edwards, Ruth Lewis, Clare Wilkinson   +12 more
doaj   +1 more source

Multi-axis manual controllers: A state-of-the-art report [PDF]

, 1981
A literature search was carried out to examine the feasibility of a six degree of freedom hand controller. Factors addressed included related areas, approaches to manual control, applications of manual controllers, and selected studies of the human ...
King, M. L., Lippay, A., Mckinnon, G. M.
core   +1 more source

Studies of the $\omega$ meson with the KLOE detector

, 2015
The paper presents status of three studies involving the $\omega$ meson using data collected by the KLOE detector. The first two projects are feasibility studies performed on simulated data concerning an upper limit measure ment of BR($\Phi \to \omega ...
Andersson, W. Ikegami, Heijkenskjöld, L.   +1 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Satellite animal tracking feasibility studies [PDF]

A study was initiated in Tsavo National Park to determine movements and home ranges of individual elephants and their relations to overall distribution patterns and environmental factors such as rainfall. Methods used were radio tracking and observations
Buechner, H. K.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Feasibility study questions [PDF]

British Journal of Anaesthesia, 2016
K L, Railton, S, Anwar
openaire   +2 more sources

Feasibility Studies for the Panda Experiment at Fair [PDF]

, 2010
PANDA, the detector to study AntiProton ANnihilations at DArmstadt, will be installed at the future international Facility for Anti-proton and Ion Research (FAIR) in Darmstadt, Germany.
Biegun, A.
core   +1 more source

Nuclear collisions at the Future Circular Collider

, 2016
The Future Circular Collider is a new proposed collider at CERN with centre-of-mass energies around 100 TeV in the pp mode. Ongoing studies aim at assessing its physics potential and technical feasibility.
Armesto, N., d'Enterria, D., Dainese, A., Masciocchi, S., Roland, C., Salgado, C. A., van Leeuwen, M., Wiedemann, U. A.   +7 more
core   +1 more source