Results 111 to 120 of about 145,410 (301)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
VaccinesDespite the use of direct-acting antiviral medications to treat hepatitis C virus (HCV), over a million people are newly infected each year, highlighting the need for a prophylactic vaccine.
Nicole E. Skinner
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Tradeoff directions in multiobjective optimization problems [PDF]
, 1997 Multiobjective optimization problems (MOP) typically have conflicting objectives wherein a gain in one objective is at the expense of another. Tradeoff directions, which measure the change in some objectives relative to changes in others, provide ...
Henig, Mordechai I., Buchanan, John T.
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A computer code for solving medium sized non-linear programming problems by the method of feasible directions. [PDF]
, 1974 A computer code, FEASBL, is developed to maximize a non-linear objective function over a convex feasible region. The feasible region is defined by a set of non-linear and linear constraints on the variables.
Harrison, James Douglas.
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A Survey on Automated Pain Recognition and Assessment Using Multimodal
Cybernetics and Information TechnologiesPractical pain assessment is essential in clinical practice. However, conventional methods for pain assessment depend primarily on patients’ self-reports, which are not feasible for non-communicative individuals, such as neonates and unconscious patients.
Jasim Wala’a N., Chyad Adala Mahdi
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Holding Corporate Social Responsibility to account: its applicability in tourism development [PDF]
Tourism was introduced in Elmina and Cape Coast, (Ghana, Africa) home to three World Heritage Sites (slave dungeons during transatlantic slave trade) as a means to poverty reduction. However, almost fifteen years later, this was not achieved.
Koutra, Christina
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Feasible Direction Methods for Constrained Nonlinear Optimization : Suggestions for Improvements [PDF]
, 2007 This thesis concerns the development of novel feasible direction type algorithms for constrained nonlinear optimization. The new algorithms are based upon enhancements of the search direction determination and the line search steps.
Mitradjieva-Daneva, Maria
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