Results 81 to 90 of about 809,365 (289)
Design of cylindrical honeycomb cores – Geometric consideration –
Mechanical Engineering Journal, 2018 Lightweight and rigid honeycomb cores have a feature as deployable structures, i.e., their shapes can be changed as desired from the viewpoint of manufacturing processes.
Sachiko ISHIDA
doaj +1 more source
Experimental investigation of an interior search method within a simple framework [PDF]
, 1986 A steepest gradient method for solving Linear Programming (LP) problems, followed by a procedure for purifying a non-basic solution to an improved extreme point solution have been embedded within an otherwise simplex based optimiser.
Mitra, G, Tamiz, M, Yadeger, J
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Edges vs Circuits: a Hierarchy of Diameters in Polyhedra [PDF]
, 2014 The study of the graph diameter of polytopes is a classical open problem in polyhedral geometry and the theory of linear optimization. In this paper we continue the investigation initiated in [4] by introducing a vast hierarchy of generalizations to the ...
Borgwardt, Steffen +2 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Optimality Conditions for Approximate Solutions in Multiobjective Optimization Problems
Journal of Inequalities and Applications, 2010 We study first- and second-order necessary and sufficient optimality conditions for approximate (weakly, properly) efficient solutions of multiobjective optimization problems. Here, tangent cone, -normal cone, cones of feasible directions, second-order
Lee HeungWingJoseph +2 more
doaj
Feasible Direction Decomposition Algorithms for Training Support Vector Machines [PDF]
Machine Learning, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Attenuation of Motorcycle Handle Vibration Using Dynamic Vibration Absorber
MATEC Web of Conferences, 2018 Motorcycle riders are exposed to hand-transmitted vibration of the hand-arm system due to the vibration of the handle and extended exposure can result in numbness and trembling.
Saifudin Muhammad Iyad Al-Maliki +2 more
doaj +1 more source