Results 81 to 90 of about 6,356,098 (354)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dynamic Feature Engineering for Adaptive Fraud Detection

Engineering Proceedings
In today’s digital economy, electronic payments are essential to supporting financial transactions. However, the danger of fraud also rises with company complexity and volume.
Ajay Sharma, Shamneesh Sharma, Arun Malik, Rajeev Sobti, Anang Suryana   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Social Embeddedness and Agent Development [PDF]

, 1998
Two different reasons for using agents are distinguished: the `engineering' perspective and the `social simulation' perspective. It is argued that this entails some differences in approach.
Edmonds, Bruce
core  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The Answer is in the Text: Multi-Stage Methods for Phishing Detection Based on Feature Engineering

IEEE Access, 2020
A phishing attack is a threat based on fraudulent communication, usually by e-mail, where the cybercriminals, impersonating a trusted person or organization, try to lure and coax a target. Phishing detection approaches that obtain highly representational
Eder Souza Gualberto, Rafael Timoteo De Sousa, Thiago Pereira De Brito Vieira, Joao Paulo Carvalho Lustosa Da Costa, Claudio Gottschalg Duque   +4 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Using Feature‐Assisted Machine Learning Algorithms to Boost Polarity in Lead‐Free Multicomponent Niobate Alloys for High‐Performance Ferroelectrics

Advanced Science, 2022
To expand the unchartered materials space of lead‐free ferroelectrics for smart digital technologies, tuning their compositional complexity via multicomponent alloying allows access to enhanced polar properties.
Seung‐Hyun Victor Oh, Woohyun Hwang, Kwangrae Kim, Ji‐Hwan Lee, Aloysius Soon   +4 more
doaj   +1 more source

Feature Generation by Convolutional Neural Network for Click-Through Rate Prediction

, 2019
Click-Through Rate prediction is an important task in recommender systems, which aims to estimate the probability of a user to click on a given item. Recently, many deep models have been proposed to learn low-order and high-order feature interactions ...
Chen, Yingzhi, Guo, Huifeng, Liu, Bin, Tang, Ruiming, Yu, Jinkai, Zhang, Yuzhou   +5 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source