Results 81 to 90 of about 310,518 (314)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

SiamDCFF: Dynamic Cascade Feature Fusion for Vision Tracking

Sensors
Establishing an accurate and robust feature fusion mechanism is key to enhancing the tracking performance of single-object trackers based on a Siamese network.
Jinbo Lu, Na Wu, Shuo Hu
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

3DPyranet Features Fusion for Spatio-temporal Feature Learning

CoRR
Convolutional neural network (CNN) slides a kernel over the whole image to produce an output map. This kernel scheme reduces the number of parameters with respect to a fully connected neural network (NN). While CNN has proven to be an effective model in recognition of handwritten characters and traffic signal sign boards, etc.
Ihsan Ullah 0002, Alfredo Petrosino
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Multi-Layers Feature Fusion of Convolutional Neural Network for Scene Classification of Remote Sensing

IEEE Access, 2019
Remote sensing scene classification is still a challenging task in remote sensing applications. How to effectively extract features from a dataset with limited scale is crucial for improvement of scene classification.
Chenhui Ma, Xiaodong Mu, Dexuan Sha
doaj   +1 more source

Feature-Level Multi-focus Image Fusion using Neural Network and Image Enhancement

, 2012
Image Processing applications have grown vastly in real world. Commonly due to limited depth of optical field lenses, it becomes inconceivable to obtain an image where all the objects are in focus.
Dr. G. Mamatha, Cyril Prasanna Raj, Shaik Abdul Rahim   +2 more
core  

Feature Fusion Based SVM Classifier for Protein Subcellular Localization Prediction

, 2016
For the importance of protein subcellular localization in different branches of life science and drug discovery, researchers have focused their attentions on protein subcellular localization prediction.
Ben Islam, Md Khaled, Mondal, Md Nazrul Islam, Al Mehedi, Md, Rahman, Julia   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source