Results 91 to 100 of about 946,604 (274)
vDNN: Virtualized Deep Neural Networks for Scalable, Memory-Efficient Neural Network Design
, 2016 The most widely used machine learning frameworks require users to carefully tune their memory usage so that the deep neural network (DNN) fits into the DRAM capacity of a GPU. This restriction hampers a researcher's flexibility to study different machine
Clemons, Jason +4 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Crack Defect Detection Method for Plunge Pool Corridor Based on the Improved U-Net Network
Applied SciencesCrack defects pose a significant threat to the safe operation of the foundational structures of hydropower stations. Therefore, crack detection in a plunge pool corridor is crucial for the safe operation and maintenance of hydropower hubs.
Chunyao Hou +5 more
doaj +1 more source
Effect Size Estimation and Misclassification Rate Based Variable Selection in Linear Discriminant Analysis [PDF]
, 2012 Supervised classifying of biological samples based on genetic information, (e.g. gene expression profiles) is an important problem in biostatistics. In order to find both accurate and interpretable classification rules variable selection is indispensable.
Klaus, Bernd
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
On the Benefit of Using Time Series Features for Choosing a Forecasting Method [PDF]
In research of time series forecasting, a lot of uncertainty is still related to the question of which forecasting method to use in which situation. One thing is obvious: There is no single method that performs best on all time series.
Gabrys, Bogdan, Lemke, Christiane
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Synapse clusters are preferentially formed by synapses with large recycling pool sizes.
PLoS ONE, 2010 Synapses are distributed heterogeneously in neural networks. The relationship between the spatial arrangement of synapses and an individual synapse's structural and functional features remains to be elucidated.
Oliver Welzel +7 more
doaj +1 more source
Understanding the Fine Structure of Electricity Prices. [PDF]
This paper analyzes the special features of electricity spot prices derived from the physics of this commodity and from the economics of supply and demand in a market pool.
Geman, Hélyette, Roncoroni, Andréa
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source