Results 101 to 110 of about 2,076,683 (280)

A construction of heterogeneous transfer learning model based on associative fusion of image feature data

open access: yesScientific Reports
Source images and predicted target images differ in image features. When heterogeneous transfer learning is applied some difficulties and further issues appear. For example, noise in image recognition appears and is required to be reduced.
Wen-Fei Tian   +3 more
doaj   +1 more source

AGN Dusty Tori as a Clumpy Two-Phase Medium: The 10 Micron Silicate Feature

open access: yes, 2011
We investigated the emission of active galactic nuclei dusty tori in the infrared domain, with a focus on the 10 micron silicate feature. We modeled the dusty torus as a clumpy two-phase medium with high-density clumps and a low-density medium filling ...
Baes, Maarten   +4 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Feature-Based Federated Transfer Learning: Communication Efficiency, Robustness and Privacy

open access: yesIEEE Transactions on Machine Learning in Communications and Networking
In this paper, we propose feature-based federated transfer learning as a novel approach to improve communication efficiency by reducing the uplink payload by multiple orders of magnitude compared to that of existing approaches in federated learning and ...
Feng Wang   +2 more
doaj   +1 more source

Feature variability determines specificity and transfer in multiorientation feature detection learning

open access: yesJournal of Vision
Historically, in many perceptual learning experiments, only a single stimulus is practiced, and learning is often specific to the trained feature. Our prior work has demonstrated that multi-stimulus learning (e.g., training-plus-exposure procedure) has the potential to achieve generalization. Here, we investigated two important characteristics of multi-
Zhu, Jun-Ping, Zhang, Jun-Yun
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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