Anaphylactic Transfusion Reaction to Washed Packed Red Blood Cells (pRBCs)
The annual blood transfusions in the United States exceed 16 million units, and 1% of the cases experience adverse events. Febrile nonhemolytic transfusion reaction is most common accounting for 1%–3% of the cases.
Schaza Javed Rana +3 more
doaj +2 more sources
Characterization of pediatric transfusion-dependent thalassemia patients in a large academic center. [PDF]
Schematic presentation of antibodies detected in pediatric transfusion‐dependent thalassemia patients. Abstract Background Transfusion‐dependent thalassemia patients are at high risk of transfusion‐related complications. Yet, there is scanty data on the frequency of transfusion reactions, particularity alloimmunization among pediatric transfusion ...
Zarrabian D, Hanna M.
europepmc +2 more sources
Retrospective Evaluation of Blood Product Transfusion Outcomes and Risk Factors for Transfusion Reactions in Dogs at a Veterinary Teaching Hospital With an Established Blood Bank: 137 Dogs (2018-2022). [PDF]
ABSTRACT Objective To evaluate the outcome of blood transfusions in dogs and identify the incidence of and risk factors associated with transfusion reactions (TRs) classified according to the Association of Veterinary Hematology and Transfusion Medicine (AVHTM) consensus.
Holm NG, Nielsen LN, Langhorn R.
europepmc +2 more sources
A prospective multicenter observational study assessing incidence and risk factors for acute blood transfusion reactions in dogs. [PDF]
Abstract Background Reported incidence of blood transfusion reactions (TR) varies greatly. Objective To prospectively evaluate the incidence of acute TRs in dogs receiving allogenic blood products, using consensus definitions, and to assess factors associated with TRs.
Hall GBF +18 more
europepmc +2 more sources
Effect of N-Acetylcysteine, Ascorbic Acid, and a Vitamin E Analog on Oxidative and Storage Lesions in Canine Packed Red Blood Cells. [PDF]
ABSTRACT Objective To describe storage and oxidative lesions in canine packed red blood cells (pRBCs) during routine storage with additives, including saline, N‐acetylcysteine (NAC), ascorbic acid (AA), and vitamin E analog (VE). Design Prospective, comparative study of canine pRBCs with or without antioxidant additives during routine 42‐day storage ...
Roque-Torres JL +5 more
europepmc +2 more sources
Feeling the burn: the significant burden of febrile nonhemolytic transfusion reactions [PDF]
BACKGROUNDFebrile nonhemolytic transfusion reactions (FNHTRs) are characterized by a post‐transfusion temperature rise (of ≥ 1°C, to ≥ 38°C) or chills/rigors unrelated to the underlying condition. FNHTRs are provoked by inflammatory cytokines in the product or by host antileukocyte antibodies against residual donor leukocytes. FNHTRs are among the most
Robert, Cohen +8 more
openaire +2 more sources
Study of the incidence and profile of acute transfusion reactions in children
Background: Blood is a vital human tissue and a precious health resource. Use of these components may be associated with adverse events, which compromise the efficiency and safety of blood transfusion.
Sithara Subair +2 more
doaj +1 more source
Febrile Nonhemolytic Transfusion Reactions
Abstract Context.—Febrile nonhemolytic transfusion reactions (FNHTRs) cause unwelcome interruptions during the course of blood product transfusions and necessitate measures to verify the nature of the reaction and to exclude certain dangerous reactions, such as hemolytic and septic phenomena.
Christian N. Ezidiegwu +4 more
openaire +1 more source
Abstract Objectives To describe the administration of lyophilized canine albumin (LCA) and determine the increase in serum albumin concentrations post‐LCA transfusion. To describe the incidence and types of acute transfusion reactions (TRs) and associated outcome in dogs presenting to a veterinary teaching hospital. Design Retrospective and descriptive
Emilia Terradas Crespo +2 more
wiley +1 more source
Acetaminophen and Diphenhydramine Premedication for Allergic and Febrile Nonhemolytic Transfusion Reactions: Good Prophylaxis or Bad Practice? [PDF]
Febrile nonhemolytic and allergic reactions are the most common transfusion reactions, but usually do not cause significant morbidity. In an attempt to prevent these reactions, US physicians prescribe acetaminophen or diphenhydramine premedication before more than 50% of blood component transfusions.
Terrence L, Geiger, Scott C, Howard
openaire +2 more sources

