Assessing willingness to pay for HLA-B*58:01 genetic testing before allopurinol initiation and its potential impact on future health policy, Thailand. [PDF]
Towiwat P +4 more
europepmc +1 more source
Preinfusion Glucocorticoid Reduction and Elimination in Patients With Uncontrolled Gout on Pegloticase and Methotrexate: A Case Series. [PDF]
Albert J +3 more
europepmc +1 more source
Firsekibart for steroid withdrawal in glucocorticoid-dependent refractory gout: a case report. [PDF]
Tan J +5 more
europepmc +1 more source
Research progress on multidimensional intervention strategies for hyperuricemia: Western medicine, Traditional Chinese Medicine, and emerging therapies. [PDF]
Li X +9 more
europepmc +1 more source
Bioequivalence evaluation of generic febuxostat versus Feburic<sup>®</sup> in healthy Chinese subjects: a randomized crossover study. [PDF]
Wang F +8 more
europepmc +1 more source
Acute cardiovascular events after discontinuation of xanthine oxidase inhibitors: a cohort study. [PDF]
Magagnoli J +4 more
europepmc +1 more source
Switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, may substantially reduce serum urate levels, through URAT1 inhibition, potentially without adversely affecting ABCG2 function: findings from the SWITCH SURI study. [PDF]
Osonoi T +7 more
europepmc +1 more source
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Mit Febuxostat steht eine Alternative zu Allopurinol zur Verfügung. Seine Wirkung auf die Harnsäurespiegel ist gut dokumentiert; ob das Mittel in Bezug auf die praktisch relevanten Gichtsymptome ebenbürtig ist oder besser abschneidet, ist bisher nicht klar.
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*Febuxostat is an orally administered, non-purine, selective inhibitor of xanthine oxidase approved for the management of chronic hyperuricaemia in patients with gout. *In a randomized, double-blind, dose-ranging study in patients with gout and hyperuricaemia, significantly more recipients of febuxostat 40-120 mg/day than placebo had serum urate levels
Philip I, Hair +2 more
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Around 1.4% of the UK population have gout, the prevalence of which increases with age to around 3% in women and 7% in men aged over 75 years.1–3 Acute gout is intensely painful and can reduce patients’ quality of life.2,3 It occurs when the serum uric acid concentration (SUA) rises (hyperuricaemia) and persists above the solubility threshold of ...
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