Impaired exocrine pancreatic function in different stages of type 1 diabetes
Introduction Aim of this study was to investigate the pancreatic exocrine function in patients with type 1 diabetes (T1D) by multiple non-invasive tests.Research design and methods The study is a single-center, cross-sectional study of pancreatic ...
Giulia Martina Cavestro +13 more
doaj +1 more source
Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis [PDF]
Die Diskussion am Ende des Artikels wurde gelöscht (§137l UrhG).Background The proteolytic enzyme elastase released by granulocytes (polymorphonuclear leukocytes [PMN]) in high concentrations during sepsis causes degradation of essential plasma proteins,
Schildberg, Friedrich-Wilhelm +7 more
core +1 more source
Calprotectina fecal e elastase-1 fecal como marcadores inflamatórios intestinais e de função pancreática na fibrose cística [PDF]
Orientador(a): Prof.(a). Dr.(a). Nelson Augusto Rosário FilhoDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Medicina Interna e Ciências da Saúde.
Lazzarotto, Eduarda Sampaio
core +1 more source
Fecal elastase-1 and ultrasonography for assessment of exocrine pancreatic function in children with cystic fibrosis [PDF]
Background: Cystic fibrosis (CF) is an autosomal recessive disorder affecting the exocrine functions of many organs including the pancreas. Clinical and laboratory recognition of pancreatic insufficiency is important for proper treatment.
Khalid Salah +4 more
doaj +1 more source
Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia [PDF]
Heterozygous mutations in neutrophil elastase have been detected in many sporadic cases of congenital neutropenia. However, a convincing pathogenetic mechanism has not been established, and it is unclear whether the effects of the mutant enzyme occur ...
Ancliff, PJ +13 more
core +1 more source
Objective. This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas–kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia. Methods. A total of 19
Guanghui Pei +4 more
doaj +1 more source
Exocrinous function of pancreas in Crohn’s disease patients
The functional state of pancreas in patients with the Crohn’s disease was studied. In feces of patients with CD, irritable colon syndrome, and healthy persons, the daily fat amount was determined by the van de Kamer’s method and fecal elastase-1 was ...
V. A. Burkovskaya
doaj +1 more source
Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin alpha(v)beta(3)-Mediated FGF-2 Release [PDF]
Background/Aims: Laminar shear stress is an important stimulus in the endothelium-dependent control of vascular tone and of vascular remodeling processes.
Hennig, Theres +9 more
core +1 more source
Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase [PDF]
The neutrophil has been implicated as an important mediator of vascular injury, especially after endotoxemia. This study examines neutrophil-mediated injury to human microvascular endothelial cells in vitro. We found that neutrophils stimulated by formyl-
M G Tonnesen +15 more
core +1 more source
Background: Data on prevalence and burden of end-organ damage in fibrocalculous pancreatic diabetes (FCPD) from eastern India is scant. This study investigated the burden of end-organ damage and exocrine pancreatic defect in FCPD patients in Eastern ...
Beatrice Anne +5 more
doaj +1 more source

