Results 181 to 190 of about 373,383 (299)

Urinary and Faecal Amino‐Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study

International Journal of Cancer, EarlyView.
ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman, Elsa L. S. A. van Liere, Animesh Acharjee, Sudip Mondal, Eduard A. Struys, Andreas Antoniadis, Jasmijn E. B. de Boer, Shivra R. Siriram, Abdellatif Bakkali, Sofie Bosch, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Manon C. W. Spaander, Tim G. J. de Meij, Evelien Dekker, Dewkoemar Ramsoekh, Nanne K. H. de Boer   +18 more
wiley   +1 more source

Fecal Microbiome and Serum Metabolome Profiles of the Ovarian Failure Mouse Model. [PDF]

Appl Biochem Biotechnol
Fu Y, Jiang H, Peng D, Bai Z, Wang S, Liu H, Zhang W, Shang W.   +7 more
europepmc   +1 more source

Lifestyle Factors Associated With Colorectal Adenomas: Results From a Vietnamese Case–Control Study

International Journal of Cancer, EarlyView.
ABSTRACT Although colorectal cancer (CRC) is the fourth most common cancer in Vietnam, evidence on lifestyle factors associated with colorectal adenomas (CRA) remains limited. We conducted a case–control study to examine lifestyle factors associated with CRA.
Chi Thi‐Du Tran, Tuan Thanh Nguyen, Mo Thi Tran, Huong Thi‐Thu Pham, Hung Nguyen Luu, Xiao‐Ou Shu, Linh Cu Le   +6 more
wiley   +1 more source

Gut microbial immunometabolic pathways associated with cardiac arrest risk: genetic evidence and exploratory fecal microbiome profiling. [PDF]

Front Cell Dev Biol
Xie L, Hu Y, Du K, Liu K, Yang S, Zhou Y, Zhang Q, Lan C.   +7 more
europepmc   +1 more source

Human Protein Biomarkers Outperform Bacterial Proteins in Colorectal Cancer Detection

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) generally develops from precancerous adenomatous lesions, including advanced adenomas (AA), through a sequence of carcinogenic molecular alterations. The composition of the gut microbiota and the fecal proteome is known to differ between individuals with AA and CRC compared to controls, providing opportunities for ...
Roza C. M. Opperman, Sofie Bosch, Alex A. Henneman, Thang V. Pham, Sander R. Piersma, Tim G. J. de Meij, Meike de Wit, Beatriz Carvalho, Remond J. A. Fijneman, Gerrit A. Meijer, Evelien Dekker, Connie R. Jimenez, Nanne K. H. de Boer   +12 more
wiley   +1 more source

Combined abdominal and transcranial photobiomodulation is associated with fecal microbiome restructuring: a systems microbiology pre-post case report. [PDF]

Front Syst Biol
Guimarães GNF, Barrett DW, Gonzalez-Lima F.   +2 more
europepmc   +1 more source

Oral and Fecal Microbial Dysbiosis as Non‐Invasive Diagnostic Biomarkers for Gastrointestinal Cancers: A Systematic Review and Meta‐Analysis of Diagnostic Accuracy

International Journal of Cancer, EarlyView.
ABSTRACT Gastrointestinal (GI) cancers, including esophageal (EC), gastric (GC), and colorectal cancer (CRC), impose a substantial global burden, with early detection remaining crucial for improving patient outcomes. The oral and gut microbiota are increasingly implicated in cancer development and hold promise as sources of non‐invasive biomarkers ...
Saidi Hu, Zhouyan Chen, Yanxia Li, Qingyan Liao, Mingdong Luo, Danyang Song, Hanyue Yu, Yuetong Gao, Shuanglong Yang, Siran Wan, Shunhong Zhang, Chenchen Luo, Lin‐Yong Zhao   +12 more
wiley   +1 more source

Fecal microbiome transplant in food allergy in humans and mice identifies a role for bile acid metabolites in oral tolerance. [PDF]

Sci Transl Med
Rachid R, Martinez-Blanco M, Kuziel GA, Stephen-Victor E, Groussin M, Orakov A, Russell G, Nguyen LTT, Poyet M, Mukhatayev Z, Yee CSK, Albuhairi S, Kteish R, Rahman EA, Farraj FA, Wang Z, Dahlberg S, Ryan M, Fitzgerald M, Elverson W, Lee JJ, Schneider L, MacGinnitie A, Crestani E, Queheillalt D, Burke-Roberts E, Watson J, Elliott RJ, Wong WF, Osman M, Voyksner R, Hohmann E, Huttenhower C, Alm E, Rakoff-Nahoum S, Chatila TA.   +35 more
europepmc   +1 more source

Addressing the Abundance Paradox Through Topology‐Guided Graph Learning for Cross‐Cohort Classification of Type 2 Diabetes

iMetaMed, EarlyView.
By shifting from highly variable taxonomic abundance to conserved ecological network topologies, our Dual‐Stream Graph Attention Network (DS‐GAT‐CP) resolves the “abundance paradox,” enabling highly accurate and cross‐regionally robust non‐invasive screening for Type 2 Diabetes. ABSTRACT Gut microbiome‐based machine learning models for Type 2 Diabetes (
Changjian Wu, Ping Wei, Xuhui Wang, Hua Hua, Junli Li   +4 more
wiley   +1 more source

Impact of ceftiofur administration and <i>Escherichia coli</i> inoculation on the calf fecal microbiome. [PDF]

mSystems
Sommer AJ, Ferrandis-Vila M, Mamerow S, Berens C, Menge C, Wei S, Wang Q, Aarestrup FM, Otani S, Sapountzis P.   +9 more
europepmc   +1 more source