Results 91 to 100 of about 80,269 (322)

The Brain-Gut-Microbiome Axis. [PDF]

, 2018
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir, Martin, Clair R, Mayer, Emeran A, Osadchiy, Vadim   +3 more
core   +2 more sources

Fecal microbiota transplantation is safe and tolerable in patients with multiple sclerosis: A pilot randomized controlled trial

Multiple sclerosis journal - experimental, translational and clinical, 2022
Background Patients with MS have an altered gut microbiota compared to healthy individuals, as well as elevated small intestinal permeability, which may be contributing to the development and progression of the disease. Objective We sought to investigate
K. Al, Laura J. Craven, Shaeley Gibbons, S. Parvathy, Ana Christina Wing, C. Graf, Kate A Parham, Steven M. Kerfoot, Hannah Wilcox, J. Burton, M. Kremenchutzky, S. Morrow, C. Casserly, J. Meddings, Manas Sharma, M. Silverman   +15 more
semanticscholar   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Probiotic administration in congenital heart disease: a pilot study. [PDF]

, 2013
ObjectiveTo investigate the impact of probiotic Bifidobacterium longum ssp. infantis on the fecal microbiota and plasma cytokines in neonates with congenital heart disease.Study designSixteen infants with congenital heart disease were randomly assigned ...
Bokulich, NA, Ellis, CL, Elumalai, J, Haapanen, L, Kalanetra, KM, Mills, DA, Mirmiran, M, Raff, G, Rutledge, JC, Schegg, T, Underwood, MA   +10 more
core   +2 more sources

Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients [PDF]

, 2022
Dafa Ding, Huijuan Yong, You Na, Wei Lu, Yang Xu, Xiaolong Ye, Yayun Wang, Tingting Cai, Xiaoling Zheng, Hui Chen, Bota Cui, Faming Zhang, Xingyin Liu, Jian‐Hua Mao, Yibing Lu, Hang Chang   +15 more
openalex   +1 more source

Gut Dysbiosis and Fecal Microbiota Transplantation in Autoimmune Diseases

International Journal of Molecular Sciences, 2022
Gut microbiota dysbiosis has recently been reported in a number of clinical states, including neurological, psychiatric, cardiovascular, metabolic and autoimmune disorders. Yet, it is not completely understood how colonizing microorganisms are implicated
Paulína Belvončíková, M. Marônek, R. Gardlík   +2 more
semanticscholar   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Evaluation of an Antibiotic Cocktail for Fecal Microbiota Transplantation in Mouse [PDF]

, 2022
Jijun Tan, Jiatai Gong, Feng‐Cheng Liu, Baizhen Li, Zhanfeng Li, Jiaming You, He Jianhua, Shusong Wu   +7 more
openalex   +1 more source

Encyclopedia of fecal microbiota transplantation: a review of effectiveness in the treatment of 85 diseases

Chinese Medical Journal, 2022
Fecal microbiota transplantation (FMT) has been used as a core therapy for treating dysbiosis-related diseases by remodeling gut microbiota. The methodology and technology for improving FMT are stepping forward, mainly including washed microbiota ...
Yun Wang, Shenmin Zhang, T. Borody, Faming Zhang   +3 more
semanticscholar   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source