Results 61 to 70 of about 80,269 (322)

Long-term impact of fecal transplantation in healthy volunteers [PDF]

, 2019
Fecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI). Success of FTM in treatment of rCDI led to a number of studies investigating the effectiveness of its ...
Egozcue Rubí, Juan José, Goloshchapov, Oleg V., Olekhnovich, Evgenii I., Sidorenko, Sergey V.   +3 more
core   +2 more sources

Pilot evaluation of a single oral fecal microbiota transplantation for canine atopic dermatitis

Scientific Reports, 2023
The gut microbiota has been suggested to be involved in the pathogenesis of canine atopic dermatitis (cAD). However, the gut microbiota has not been well characterized in dogs with atopic dermatitis (AD).
Koji Sugita, A. Shima, Kaho Takahashi, Genki Ishihara, K. Kawano, K. Ohmori   +5 more
semanticscholar   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Murine fecal microbiota transplantation lowers gastrointestinal pathogen loads and dampens pro-inflammatory immune responses in Campylobacter jejuni infected secondary abiotic mice [PDF]

, 2019
Conventional mice are protected from Campylobacter jejuni infection by the murine host-specific gut microbiota composition. We here addressed whether peroral fecal microbiota transplantation (FMT) might be an antibiotics-independent option to lower even ...
Bereswill, Stefan, Heimesaat, Markus M., Mrazek, Katharina   +2 more
core   +1 more source

Fecal microbiota transplantation and next-generation therapies: A review on targeting dysbiosis in metabolic disorders and beyond

SAGE Open Medicine
The human microbiome, particularly the gut microbiome, has emerged as a central determinant of health and disease. Dysbiosis, an imbalance in the microbial composition of the gut, is associated with a variety of metabolic and other diseases, highlighting
Zenawork Sahle, Getabalew Engidaye, Demissew Shenkute Gebreyes, Behailu Adenew, Tsegahun Asfaw Abebe   +4 more
semanticscholar   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Effect of Vegan Fecal Microbiota Transplantation on Carnitine‐ and Choline‐Derived Trimethylamine‐N‐Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundIntestinal microbiota have been found to be linked to cardiovascular disease via conversion of the dietary compounds choline and carnitine to the atherogenic metabolite TMAO (trimethylamine‐N‐oxide).
Loek P. Smits, Ruud S. Kootte, Evgeni Levin, Andrei Prodan, Susana Fuentes, Erwin G. Zoetendal, Zeneng Wang, Bruce S. Levison, Maartje C. P. Cleophas, E. Marleen Kemper, Geesje M. Dallinga‐Thie, Albert K. Groen, Leo A. B. Joosten, Mihai G. Netea, Erik S. G. Stroes, Willem M. de Vos, Stanley L. Hazen, Max Nieuwdorp   +17 more
doaj   +1 more source

Species and genus level resolution analysis of gut microbiota in Clostridium difficile patients following fecal microbiota transplantation [PDF]

, 2014
BACKGROUND: Clostridium difficile is an opportunistic human intestinal pathogen, and C. difficile infection (CDI) is one of the main causes of antibiotic-induced diarrhea and colitis.
Alexander Khoruts, Amanda Kilburn, Matthew J Hamilton, Michael J Sadowsky, Oleg Paliy, Tatsuya Unno, Vijay Shankar   +6 more
core   +2 more sources

Fecal Microbiota Transplantation: Insights into Colon Carcinogenesis and Immune Regulation

Journal of Clinical Medicine
Colorectal cancer (CRC) constitutes a significant global health challenge, with recent studies underscoring the pivotal role of the gut microbiome in its pathogenesis and progression.
O. Brusnic, D. Onisor, A. Boicean, Adrian Hașegan, Cristian Ichim, Andreea Guzun, R. Chicea, Samuel-Bogdan Todor, B. Vintilă, Paula Anderco, Corina Porr, Horațiu Dura, S. Fleacă, A. Cristian   +13 more
semanticscholar   +1 more source